Reference

Maackiain derivatives

Maackiain derivatives. (Suntry Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59013784 A2 24 Jan 1984 Showa, 10 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C07D493-14. ICI: C07D493-14, C07D307-00, C07D311-00, C07D317-00. APPLICATION: JP 82-123326 14 Jul 1982. DOCUMENT TYPE: Patent CA Section: 26 (Biomolecules and Their Synthetic Analogs) Maackiains I (R = HOCH2CMe:CHCH2, R1 = H)(II) and III (R2 = H, R3 = HOCH2CHMeCH2CH2)(IV) were prepd. Thus, II was prepd. by condensation of maackiain (I; R = R1 = H) with H2C:CHCH2Br, allyl rearrangement of I (R = H, R1 = allyl), oxidn. of I (R = allyl, R1 = H) with OsO4 and NaIO4, condensation of I (R = OCHCH2, R1 = H) with EtO2CCMe:PPh3, and redn. of I (R = EtO2CCMe:CHCH2, R1 = H) with LiAlH4. IV was prepd. by cyclocondensation of benzopyran V with benzodioxolanylmercury VI, redn. of III (R2 = benzyl, R3 = MeO2C) with LiAlH4, oxidn. of III (R2 = benzyl, R3 = HOCH2) with MnO2, condensation of III (R2 = benzyl, R3 = formyl) with HOCH2CHMeCH:PPh3, and hydrogenolysis of III (R2 = benzyl, R3 = HOCH2CHMeCH:CH) with H in the presence of 10% Pd/C.Chemical with cas number 5717-37-3 also plays role. .

Synthesis of 3,5-dihydroxy-2,4-dimethylheptanoic acid d-lactone in enantiomerically pure form

Synthesis of 3,5-dihydroxy-2,4-dimethylheptanoic acid d-lactone in enantiomerically pure form. Chakraborty, Tushar Kanti; Tapadar, Subbasish; Roy, Saumya (Indian Institute of Chemical Technology, Hyderabad 500 007, India). ARKIVOC (Gainesville, FL, United States), (3), 170-178 (English) 2005 Arkat USA Inc. URL: http://www.arkat-usa.org/ark/journal/2005/I03_Rao/1190/1190.pdf. CODEN: AGFUAR. DOCUMENT TYPE: Journal; (online computer file) CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Radical-mediated opening of a chiral trisubstituted epoxy alc. using cp2TiCl was followed by diastereoselective redn. of the resulting olefinic diol to build all the chiral centers of 3,5-dihydroxy-2,4-dimethylheptanoic acid d-lactone (I) with the desired stereochem. leading to the total synthesis of this highly substituted d-lactone.In this study，5717-37-3 is also used. .