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CAS No.: | 57197-43-0 |
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Name: | co-trifamole |
Molecular Structure: | |
Formula: | C14H18N4O3•C11H13N3O3S |
Molecular Weight: | 557.69 |
Synonyms: | co-trifamole |
Density: | g/cm3 |
Boiling Point: | 526°Cat760mmHg |
Flash Point: | 271.9°C |
Safety: | Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx. See also AROMATIC AMINES and AMIDES. |
PSA: | 213.57000 |
LogP: | 4.52720 |
IUPAC Name: 4-Amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide ; 5-[(3,4,5-Trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Synonyms: Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine ; Co-trifamole ;Nevin (mixture) ; Sulfamoxazole + trimethoprim ;Sulfamoxole and trimethoprim
CAS NO: 57197-43-0
Molecular Formula of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) : C25H31N7O6S
Molecular Weight of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) : 557.6219
Molecular Structure of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) :
Flash Point: 271.9 °C
Enthalpy of Vaporization: 80.02 kJ/mol
Boiling Point: 526 °C at 760 mmHg
Vapour Pressure: 3.74E-11 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
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dog | LD50 | oral | > 1gm/kg (1000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976. | |
mouse | LD50 | intraperitoneal | 1870mg/kg (1870mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976. |
mouse | LD50 | oral | > 12gm/kg (12000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976. | |
rat | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976. |
rat | LD50 | oral | 14gm/kg (14000mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976. |
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx. See also AROMATIC AMINES and AMIDES.