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57197-43-0

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Basic Information
CAS No.: 57197-43-0
Name: co-trifamole
Molecular Structure:
Molecular Structure of 57197-43-0 (co-trifamole)
Formula: C14H18N4O3•C11H13N3O3S
Molecular Weight: 557.69
Synonyms: co-trifamole
Density: g/cm3
Boiling Point: 526°Cat760mmHg
Flash Point: 271.9°C
Safety: Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx. See also AROMATIC AMINES and AMIDES.
PSA: 213.57000
LogP: 4.52720
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  • SULFAMOXOLE-TRIMETHOPRIM mixture

  • Casno:

    57197-43-0

    SULFAMOXOLE-TRIMETHOPRIM mixture

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, s

  •  Shandong Mopai Biotechnology Co., LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-15965530500

    Address:shandong

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  • 2-Propenoic acid,5-hydroxypentyl ester

  • Casno:

    57197-43-0

    2-Propenoic acid,5-hydroxypentyl ester

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

    Antimex Chemical Limied, was founded in 2001, we are specializing in manufacturing & researching of Active pharmaceutical Ingredients,Veterinary pharm APIs,cosmetic ingredients,and

  •  Antimex Chemical Limied

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

    Address:Room1027,No.Jinyu Road,Pudong

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Chemistry

IUPAC Name: 4-Amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide ; 5-[(3,4,5-Trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Synonyms: Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine ; Co-trifamole ;Nevin (mixture) ; Sulfamoxazole + trimethoprim ;Sulfamoxole and trimethoprim
CAS NO: 57197-43-0
Molecular Formula of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) : C25H31N7O6S
Molecular Weight of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) : 557.6219
Molecular Structure of Sulfamoxole-trimethoprim mixture (CAS NO.57197-43-0) :
Flash Point: 271.9 °C
Enthalpy of Vaporization: 80.02 kJ/mol
Boiling Point: 526 °C at 760 mmHg
Vapour Pressure: 3.74E-11 mmHg at 25°C
 

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 1gm/kg (1000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976.
mouse LD50 intraperitoneal 1870mg/kg (1870mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976.
mouse LD50 oral > 12gm/kg (12000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976.
rat LD50 intraperitoneal 2gm/kg (2000mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976.
rat LD50 oral 14gm/kg (14000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 634, 1976.

 

Safety Profile

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx. See also AROMATIC AMINES and AMIDES.