Reference

Antioxidant/prooxidant reactions of vitamin K

Antioxidant/prooxidant reactions of vitamin K. Canfield, Louise M.; Davy, Laura A.; Thomas, Gregory L. (Dep. Biochem., Texas A and M Univ., College Station, TX 77843-2471, USA). Biochem. Biophys. Res. Commun., 128(1), 211-19 (English) 1985. CODEN: BBRCA9. ISSN: 0006-291X. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Expts. were designed to measure O consumption caused by the oxidn. of linoleic acid [60-33-3]. These expts. show that vitamin K [12001-79-5] has antioxidant activity and that the redn. in linoleic acid oxidn. is directly dependent upon vitamin K concn. Conversely, vitamin K hydroquinone [572-96-3] enhances linoleic acid oxidn. in the absence of Fe catalyst, again in a concn.-dependent manner. At equimolar concns., vitamin K is ~80% as effective as vitamin E as an antioxidant. Vitamin E [1406-18-4] inhibits the oxidn. of linoleic acid catalyzed by vitamin K hydroquinone. Vitamin E also strongly inhibits vitamin K dependent formation of both vitamin K epoxide [25486-55-9] and g-carboxyglutamic acid [53445-96-8]. The significance of these observations to vitamin K action in vivo is discussed.

Inactivation of the infectivity of

Inactivation of the infectivity of .Some chemicals with cas registry numbers like 84-80-0 and 481-85-6 are also used.vphi.X174 DNA with some quinone derivatives. Komano, Tohru; Morita, Junji (Dep. Agric. Chem., Kyoto Univ., Kyoto, Japan). Nucleic Acids Res., Spec. Publ., 2(Symp. Nucleic Acids Chem., 4th, 1976), 131-3 (English) 1976. CODEN: NARPD6. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Section cross-reference(s): 6 Menadione (I) [58-27-5] inactivated the infectivity of .vphi.X174 DNA, however reduced I [481-85-6] more effectively inactivated .vphi.X174 DNA. Reduced phylloquinone [572-96-3] and ubiquinone-6 [1065-31-2] also inactivated .vphi.X174 DNA, but phylloquinone [84-80-0] did not affect .vphi.X174 DNA at <2 .times. 10-4M. Inactivation of .vphi.X174 DNA by reduced I was caused partially by DNA strand breakage. But DNA strand breakage by I was not obsd. .