Detail of "57369-32-1"

Reference

Inhibition of appressorial melanization in Pyricularia oryzae by nonfungicidal antiblast chemicals

Inhibition of appressorial melanization in Pyricularia oryzae by nonfungicidal antiblast chemicals. Yamaguchi, Isamu; Sekido, Shigeko; Misato, Tomomasa (Inst. Phys. Chem. Res., Wako 351, Japan). Nippon Noyaku Gakkaishi, 8(2), 229-32 (English) 1983. CODEN: NNGADV. ISSN: 0385-1559. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) Accumulation of 2-hydroxyjuglone (I) [4923-55-1], scytalone [49598-85-8], and riboflavin [83-88-5] was obsd. in P. oryzae culture treated with tricyclazole (II) [41814-78-2], CGA 49104 (III) [57369-32-1], 4,5,6,7-tetrachlorophthalide (IV) [27355-22-2], or 2,3,4,5,6-pentachlorobenzyl alc. [16022-69-8] during appressorial maturation, effects of II and III being particularly marked. II, III, and IV did not inhibit the mycelial growth or the cellulase [9012-54-8] activity in P. oryzae culture. Vermelone [59796-04-2] and 1,8-dihydroxynaphthalene [569-42-6] depressed the inhibitory effect of III on appressorial penetration into cellophane film at 0.1 mM, but inhibited the penetration at 0. 9012-54-8 and 4923-55-1 which are cas registry numbers of substances are two of reagents here.5 mM. Destruction of appressoria and inhibition of appressorial function in P. oryzae culture by abnormally accumulated I and other metabolites in the melanin synthesis pathway are suggested. .

Melanin biosynthesis as a prerequisite for penetration by appressoria of Colletotrichum lagenarium: site of inhibition by melanin-inhibiting fungicides and their action on appressoria

Melanin biosynthesis as a prerequisite for penetration by appressoria of Colletotrichum lagenarium: site of inhibition by melanin-inhibiting fungicides and their action on appressoria. Kubo, Yasuyuki; Suzuki, Kazumi; Furusawa, Iwao; Yamamoto, Masaski (Fac. Agric., Kyoto Univ., Kyoto 606, Japan). Pestic. Biochem. Physiol., 23(1), 47-55 (English) 1985. CODEN: PCBPBS. ISSN: 0048-3575. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) Section cross-reference(s): 10, 11 Melanin biosynthesis by appressoria was studied in relation to their penetrating ability using tricyclazole [41814-78-2], pp 389 [59342-33-5], and pyroquilone [57369-32-1], and color mutants of C. lagenarium. Tricyclazole at 100 mM inhibited melanin biosynthesis by appressoria of C. lagenarium 104-T, and caused accumulation of 3,4-dihydro-4,8-dihydroxy-1(2H)-naphthalenone (DDN) [62332-73-4] in the culture medium. By contrast, DDN was not detected in culture media of tricyclazole-treated mutant 8015, which is defective in the enzyme involved in the conversion of scytalone [49598-85-8] to 1,3,8-trihydroxynaphthalene (1,3,8-THN) [7124-49-4]. Vermelone [59796-04-2] restored melanization of appressoria of albino mutant 79215 and of the parent strain 104-T treated with tricyclazole, pp 389, and pyroquilone; however, scytalone restored melanization only in appressoria of albino mutant 79215. Thus, tricyclazole, pp389, and pyroquilone inhibited the conversion of 1,3,8--THN to vermelone in the melanin biosynthetic pathway of appressoria of C. lagenarium. Colorless appressoria formed in the presence of the 3 melanin-inhibiting chems. germinated laterally on nitrocellulose membranes and rarely penetrated the membranes. On the other hand, when pigmented appressoria were restored by application of vermelone in the presence of the 3 chems., lateral germination of the appressoria was largely suppressed, and the membranes were effectively penetrated. Apparently, the major effect of tricyclazole, pp 389, and pyroquilone on appressoria of C. lagenarium, causing failure of penetration, is the inhibition of melanization. Effects of the chems. on other metabolic functions can be precluded as significant factors affecting the penetration process.