Products Categories
CAS No.: | 57399-97-0 |
---|---|
Name: | ETHYL (4-AMINOPHENYL)CARBAMATE |
Article Data: | 15 |
Molecular Structure: | |
Formula: | C9H12N2O2 |
Molecular Weight: | 180.206 |
Synonyms: | ethyl N-(4-aminophenyl)carbamate;Carbamic acid, (4-aminophenyl)-, ethyl ester; |
Density: | 1.22g/cm3 |
Melting Point: | 70 °C(Solv: chloroform (67-66-3)) |
Boiling Point: | 275.574oC at 760 mmHg |
Flash Point: | 120.463oC |
PSA: | 64.35000 |
LogP: | 2.49140 |
ethyl 4-nitrophenylcarbamate
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; ammonium formate; silica gel In methanol for 1.5h; Milling; | 99% |
With 5%-palladium/activated carbon; ammonium formate In tetrahydrofuran; water at 50℃; for 24h; Inert atmosphere; | 65% |
With 5%-palladium/activated carbon; ammonium formate In tetrahydrofuran; water at 50℃; for 24h; Inert atmosphere; | 65% |
chloroformic acid ethyl ester
4-nitro-aniline
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: chloroformic acid ethyl ester; 4-nitro-aniline With N-ethyl-N,N-diisopropylamine In ethyl acetate at 20℃; for 18h; Stage #2: With hydrogen; 5%-palladium/activated carbon In ethyl acetate at 20℃; under 2250.23 Torr; for 12h; | 90% |
Conditions | Yield |
---|---|
With hydrogen In dichloromethane at 25℃; for 16h; | 86% |
With hydrogen |
(4-nitroso-phenyl)-carbamic acid ethyl ester
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
With sodium dithionite In 1,4-dioxane; water for 0.5h; Reduction; Heating; | 79% |
ethyl N-(4-acetamidophenyl)carbamate
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: ethyl N-(4-acetamidophenyl)carbamate With boron trifluoride - methanol (1/1) In methanol for 3h; Reflux; Stage #2: With ammonia In methanol; water Cooling; | 71% |
chloroformic acid ethyl ester
N-acetyl-p-phenylenediamine
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
With 2.) acid Multistep reaction; |
1,4-phenylenediamine
A
N-(4-aminophenyl)carbamic acid ethyl ester
B
diethyl 1,4-phenylenediamine-N,N'-dicarboxylate
N-carboethoxyaniline
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 71 percent / HSO3ONO / acetic acid / 0.5 h / 0 °C 2: 79 percent / Na2S2O4 / dioxane; H2O / 0.5 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: diethyl ether; nitrous acid 2: tin; hydrochloric acid View Scheme |
N-(4-aminophenyl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
With triethylamine; mercury dichloride In N,N-dimethyl-formamide at 0 - 20℃; | 87.62% |
acetic anhydride
N-(4-aminophenyl)carbamic acid ethyl ester
ethyl N-(4-acetamidophenyl)carbamate
Conditions | Yield |
---|---|
In acetic acid for 1h; | 75% |
With acetic acid |