Detail of "57443-18-2"

CAS Number:
57443-18-2
Name:
Acetic acid,2-(dimethoxyphosphinyl)-, phenylmethyl ester
Molecular Structure:
Formula:
C₁₁H₁₅O₅P
Molecular Weight:
258.21
Synonyms:
Aceticacid, (dimethoxyphosphinyl)-, phenylmethyl ester (9CI);Benzyl dimethylphosphonoacetate;[(Oxo)dimethoxyphosphino]acetic acid benzyl ester;
Density:
1.217 g/cm³
Boiling Point:
359.4 °C at 760 mmHg
Flash Point:
184.8 °C
Appearance:
clear colorless to light brown liquid
Hazard Symbols:
Xn
Risk Codes:
36/37/38-22
Safety:
37/39-26 Details

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Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans: All Rights Reserved. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Carrillo, Romen; Leon, Leticia G.; Martin, Tomas; Martin, Victor S.; Padron, Jose M. (Instituto Universitario de Bio-Organica Antonio Gonzalez', Universidad de La Laguna, La Laguna 38206, Spain). Bioorganic & Medicinal Chemistry Letters, 16(23), 6135-6138 (English) 2006 Elsevier Ltd. CODEN: BMCLE8. ISSN: 0960-894X. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1 A series of enantiomerically pure (2R,3R)-disubstituted tetrahydropyrans, e.g., I, were synthesized. The in vitro antiproliferative activities were examd. 57443-18-2 and 918886-59-6 which are cas registry numbers of substances are two of reagents here. in the human solid tumor cell lines A2780 (ovarian cancer), SW1573 (non-small cell lung cancer), and WiDr (colon cancer). The results showed the relevance for antiproliferative activity of the a,b-unsatd. ester side chain at position 2 of the THP ring. .