CAS No.58859-46-4,1-Piperidinecarboxylicacid, 4-amino-, ethyl ester Suppliers,MSDS download

Detail of "58859-46-4"

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CAS Number:

58859-46-4

Name:

1-Piperidinecarboxylicacid, 4-amino-, ethyl ester

Superlist Name:

Ethyl 4-amino-1-piperidinecarboxylate

Molecular Structure:

Formula:

C₈H₁₆N₂O₂

Molecular Weight:

172.23 .

Synonyms:

1-(Ethoxycarbonyl)-4-aminopiperidine;1-Carbethoxy-4-aminopiperidine;4-Amino-1-(ethoxycarbonyl)piperidine;4-Aminopiperidine-1-carboxylicacid ethyl ester;[1-(Ethoxycarbonyl)piperidin-4-yl]amine;

EINECS:

261-472-3

Density:

1.082 g/cm³

Boiling Point:

256.483 °C at 760 mmHg

Flash Point:

78.333 °C

Solubility:

>500 g/L (20 °C) in water

Appearance:

clear colorless to light yellow liquid

Hazard Symbols:

Xi,

Risk Codes:

36/38-36/37/38-22

Safety:

26-36 Details

Reference

Development of a general process for the synthesis of highly substituted imidazoles: Development of a general process for the synthesis of highly substituted imidazoles. Sisko, Joseph; Mellinger, Mark (Synthetic Chemistry, GlaxoSmithKline, King of Prussia, PA 19406-0939, USA). Pure and Applied Chemistry, 74(8), 1349-1357 (English) 2002 International Union of Pure and Applied Chemistry. CODEN: PACHAS. ISSN: 0033-4545.Several reagents such as 58859-46-4 is used here. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Several highly substituted imidazoles have been under investigation at GlaxoSmithKline as potential therapies for the treatment of rheumatoid arthritis and have spawned the need for a general synthetic method for their prepn. 58859-46-4 is just another one chemical used in this study. on a multi kilogram scale. We describe herein the optimization of a general method for the prepn. of aryl-substituted tosylmethyl isocyanide (TosMIC) reagents and the ease with which they undergo [3+2] cycloaddns. with a host of imines, prepd. in situ, to generate densely functionalized imidazoles with various substitution patterns in a completely regioselective manner. ..

Development of a general process for the synthesis of highly substituted imidazoles: Development of a general process for the synthesis of highly substituted imidazoles. Sisko, Joseph; Mellinger, Mark (Synthetic Chemistry, GlaxoSmithKline, King of Prussia, PA 19406-0939, USA). Pure and Applied Chemistry, 74(8), 1349-1357 (English) 2002 International Union of Pure and Applied Chemistry. CODEN: PACHAS. ISSN: 0033-4545.Several reagents such as 58859-46-4 is used here. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Several highly substituted imidazoles have been under investigation at GlaxoSmithKline as potential therapies for the treatment of rheumatoid arthritis and have spawned the need for a general synthetic method for their prepn. 58859-46-4 is just another one chemical used in this study. on a multi kilogram scale. We describe herein the optimization of a general method for the prepn. of aryl-substituted tosylmethyl isocyanide (TosMIC) reagents and the ease with which they undergo [3+2] cycloaddns. with a host of imines, prepd. in situ, to generate densely functionalized imidazoles with various substitution patterns in a completely regioselective manner. ..

Detail of "58859-46-4"

1-Piperidinecarboxylicacid, 4-amino-, ethyl ester

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CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

CAS No.58859-46-4 Ethyl 4-amino-1-piperidinecarboxylate

Reference