Reference

The influence of preservatives on metachromatic assay of heparin

The influence of preservatives on metachromatic assay of heparin. Guven, K. C.; Ertan, G. (Fac. Pharm., Univ. Istanbul, Turk.). Zentralbl. Pharm., Pharmakother. Laboratoriumsdiagn., 123(3), 131-2 (English) 1984. CODEN: ZPPLBF. ISSN: 0049-8696. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Phenol [108-95-2] and methylparaben [99-76-3] interfered with the metachromatic assay of heparin [9005-49-6] while chlorocresol [59-50-7] and chlorobutanol [57-15-8] did not. The lmax of an azure A soln. at 620 nm (a band) was depressed at 510 nm (metachromatic B bond) by the addn. of heparin, but after addn. of phenol and methylparaben this band increased depending on the concn. of these preservatives and the a band reappeared. These interfering substances were then sepd. by preparative TLC and the remaining heparin eluted and subjected to metachromatic assay.

Microbicides for metalworking fluids

Microbicides for metalworking fluids. Paulus, W. (Werk Uerdingen, Bayer A.-G., Krefeld, Fed. Rep. Ger.). Tribol. Lubr., 19(2), 67-73 (Italian) 1984. CODEN: TRLBAE. ISSN: 0372-1213. DOCUMENT TYPE: Journal CA Section: 56 (Nonferrous Metals and Alloys) Section cross-reference(s): 4 The study proposes a comparative anal. relevant to the activity, ecol., and toxicol. aspects of 2 classes of microbicides used in in metalworking fluid prodn. Formaldehyde dereleasing substances and phenolic derivs. were considered. A wide series of toxicol. and ecotoxicol. data, derived from long experienced use, is available in the case of p-chloro-m-cresol [59-50-7]. Among the phenol derivs., a responsible choice according to the correct ecol. and toxicol. requirements is feasible.