Detail of "59290-81-2"

Reference

Anticoccidial 5-nitronicotinohydroxamic acids

Anticoccidial 5-nitronicotinohydroxamic acids. Morisawa, Yasuhiro; Kataoka, Mitsuru; Kitano, Noritoshi; Matsuzawa, Toshiaki (Sankyo Co., Ltd., Japan). Japan. Kokai JP 51101137 7 Sep 1976 Showa, 4 pp. 59290-23-2 and 59290-81-2 are cas registry numbers. These chemicals are also mentioned in this article. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K031-455. APPLICATION: JP 75-26346 4 Mar 1975. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) The anticoccidial hydroxamic acids I (R = H, Me) or their salts were prepd. Thus, 1.5 g 5-nitronicotinic acid was refluxed in SOCl2 and the product stirred with HONH2.HCl and Na2CO3 in aq. Et2O to give 0.3 g I (R = H), which (200 ppm in feed) was effective against Eimeria tenella in chickens. I (R = Me) was also effective. .