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593-82-8

Basic Information
CAS No.: 593-82-8
Name: 1,1-Dimethylhydrazine hydrochloride
Article Data: 7
Molecular Structure:
Molecular Structure of 593-82-8 (1,1-Dimethylhydrazine hydrochloride)
Formula: C2H8 N2 . Cl H
Molecular Weight: 96.5599
Synonyms: 1,1-Dimethylhydrazinehydrochloride; N,N-Dimethylhydrazine hydrochloride
Density: 0.829g/cm3
Melting Point: 85°C
Boiling Point: 63.9°Cat760mmHg
Flash Point: 1.1°C
Solubility: almost transparency
Risk Codes: R20/21; R28
Safety: Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.
PSA: 29.26000
LogP: 0.92400
Synthetic route
882037-58-3

1,2-dichlorovinyl propyl ketone

57-14-7

1,1-dimethylhydrazine

593-82-8

N,N-dimethylhydrazine hydrochloride

Conditions
ConditionsYield
In diethyl ether89%
506-59-2

N,N-dimethylammonium chloride

593-82-8

N,N-dimethylhydrazine hydrochloride

Conditions
ConditionsYield
Stage #1: N,N-dimethylammonium chloride With sodium nitrite In water at 20℃; Cooling with ice;
Stage #2: With zinc In water at 20℃; Cooling with ice;
63.2%
6439-49-2

1-(2-carbamylethyl)-1,1-dimethylhydrazinium chloride

A

593-82-8

N,N-dimethylhydrazine hydrochloride

B

6487-38-3

3-hydroxypropanoic acid sodium salt

Conditions
ConditionsYield
With sodium hydroxide for 1.5h; Heating;A 54%
B n/a
62-75-9

N-Nitrosodimethylamine

593-82-8

N,N-dimethylhydrazine hydrochloride

Conditions
ConditionsYield
With acetic acid; zinc at 25 - 30℃; Dampfdestillation und nachfolgendes Abdampfen mit Salzsaeure;
1730-69-4

dibutylchloroborane

57-14-7

1,1-dimethylhydrazine

A

14575-27-0

(n-C4H9)2BNHN(CH3)2

B

593-82-8

N,N-dimethylhydrazine hydrochloride

58758-48-8

2-(prop-2-ynyloxy)-1-naphthaldehyde

593-82-8

N,N-dimethylhydrazine hydrochloride

108120-55-4

2,2-Dimethyl-1,2,4,11c-tetrahydro-5-oxa-1-aza-2-azonia-cyclopenta[c]phenanthrene; chloride

Conditions
ConditionsYield
In ethanol for 3h; Heating;100%
19530-43-9

2-allyloxy-1-naphthaldehyde

593-82-8

N,N-dimethylhydrazine hydrochloride

108120-49-6

2,2-dimethyl-1,2,3,3a,4,11c-hexahydronaphtho<1',2':5,6>pyrano<4,3-c>pyrazolium chloride

Conditions
ConditionsYield
In ethanol for 3h; Heating;100%
593-82-8

N,N-dimethylhydrazine hydrochloride

96601-25-1

(E)-ethyl 4-(1-formyl-2-naphthoxy)but-2-enoate

108120-53-2

3-Ethoxycarbonyl-2,2-dimethyl-1,2,3,3a,4,11c-hexahydro-5-oxa-1-aza-2-azonia-cyclopenta[c]phenanthrene; chloride

Conditions
ConditionsYield
In ethanol for 3h; Heating;100%
593-82-8

N,N-dimethylhydrazine hydrochloride

131685-20-6

2-<2-(benzyloxy)ethyl>cyclopentanone

1488133-66-9

C16H24N2O

Conditions
ConditionsYield
With triethylamine In ethanol for 16h; Inert atmosphere; Reflux;98%
593-82-8

N,N-dimethylhydrazine hydrochloride

3-oxo-2-(phenylhydrazono)-3-(2-thienyl)propanal

(2Z,3Z)-3-(2,2-dimethylhydrazono)-2-(2-phenylhydrazono)-1-(thiophen-2-yl)propan-1-one

Conditions
ConditionsYield
With sodium acetate In methanol at 25℃; Inert atmosphere;97%
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    1,1-DimethylhydrazineHCl 593-82-8Appearance:solid or liquid Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/Pharmaceutical intermediates Transportation:By Sea,by Air,By courier like

    Nanjing Raymon Biotech Co., Ltd. is specialized in developing and marketing middle & high level pharmaceutical intermediates. We are supplying different categories of high-quality

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  • s-dimethylhydrazine

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    593-82-8

    s-dimethylhydrazine

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    FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the s-dimethylhydrazine, CAS:593-82-8 with the most competitive price and the best qualit

    Finetech Industry Limited is a company in England,which specializing in developing, manufacturing and marketing fine organic compounds and intermediates for the fine chemical and p

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  • 1,1-DiMethylhydrazine HCl

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    593-82-8

    1,1-DiMethylhydrazine HCl

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    1,1-DiMethylhydrazine HClAppearance:Off white to slight yellow solid Storage:Stored in shaded, cool and dry places Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:Handle with cares to avoid damaging the packages. Protect t

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Chemistry

IUPAC Name: 1,1-Dimethylhydrazine hydrochloride
Synonyms:1,1-Dimethylhydrazine hydrochloride ; 1,1-Dimethylhydrazine ; Hydrazine, 1,1-dimethyl-, hydrochloride
CAS NO: 593-82-8
Molecular Formula of 1,1-Dimethylhydrazine hydrochloride (CAS NO.593-82-8) :C2H9ClN2
Molecular Weight of 1,1-Dimethylhydrazine hydrochloride (CAS NO.593-82-8) :96.56
Molecular structure of 1,1-Dimethylhydrazine hydrochloride (CAS NO.593-82-8) :
EINECS: 209-811-6
Flash Point: 1.1 °C
Enthalpy of Vaporization: 30.6 kJ/mol
Boiling Point: 63.9 °C at 760 mmHg
Vapour Pressure: 168 mmHg at 25°C
Melting point: 85°C

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 96mg/kg (96mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 intraperitoneal 466mg/kg (466mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 intravenous 402mg/kg (402mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: REGIDITY

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
mouse LD50 oral 426mg/kg (426mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 intraperitoneal 210mg/kg (210mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 intravenous 191mg/kg (191mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.
rat LD50 oral 196mg/kg (196mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
AMA Archives of Industrial Health. Vol. 13, Pg. 34, 1956.

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Risk Statements 20/21-28
R20/21:Harmful by inhalation and in contact with skin. 
R28:Very toxic if swallowed.
Safety Statements 22-36/37/39-45
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS MV2900000

Standards and Recommendations

NIOSH REL: (Hydrazines) CL 0.15 mg/m3/2H