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Detail of "5932-53-6"

  • MSDS Download
  • CAS Number:
  • 5932-53-6
  • Name:
  • 8-Azabicyclo[3.2.1]octan-3-one,6-hydroxy-8-methyl-, (1R,5R,6S)-rel-

  • Superlist Name:
  • (+/-)-exo-6-Hydroxytropinone
  • Molecular Structure:
  • Formula:
  • C8H13 N O2
  • Molecular Weight:
  • 155.1943
  • Synonyms:
  • 1aH,5aH-Tropan-3-one, 6b-hydroxy- (8CI); 8-Azabicyclo[3.2.1]octan-3-one,6-hydroxy-8-methyl-, exo-; Tropinone, 6b-hydroxy- (6CI,7CI); (?à)-6b-Hydroxytropan-3-one; (?à)-6b-Hydroxytropinone
  • EINECS:
  • 227-677-7
  • Density:
  • 1.217 g/cm3
  • Melting Point:
  • 120-121 °C(lit.)
  • Boiling Point:
  • 291.6 °C at 760 mmHg
  • Flash Point:
  • 130.1 °C
  • Appearance:
  • White powder.
  • Risk Codes:
  • 23/25
  • Safety:
  • 24 25 Details

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

Assay:≥99%  Appearance:yellow cryst...  Package:25Kg/drum,5K...Storage:Store in a t...  Transportation:Express,Air,...  Application:Pharmaceutic...

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

English Name:6-Hydroxytropinone Chemical Name:(+/-)-exo-6-Hydroxytropinone Molecular Formula:C8H13NO2 Molecular Structure: CAS:5932-53-6 Quality Standard Tests Item Standard Appearance white or almost white, crystalline powder Assay ≥99.0% Pack

Min. Order:1Kilogram

Supplier:Stone Lake Pharma Tech Co. Ltd [ China (Mainland)]

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

Product Name: (+/-)-exo-6-Hydroxytropinone CAS#:5932-53-6 Implementation of standards: Enterprise Standard Packaging specificationsPackaging specifications: 25kg / barrel

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

6-hydroxy tropinone Cas no.: 5932-53-6

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

6-HYDROXYTROPINONE

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

Supplier:AlliChem, LLC [ United States]

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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CAS No.5932-53-6 (+/-)-exo-6-Hydroxytropinone

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Reference

Narcotic antagonists
Narcotic antagonists. Synthesis and evaluation of some substituted 1,2,3,4,5,6-hexahydro-1,4:2,6-dimethano-3-benzazocines. Montzka, Thomas A.; Matiskella, John D. (Bristol Lab. Div., Bristol-Myers Co., Syracuse, N. Y., USA). J. Med.Several reagents with their cas registry numbers 61727-52-4 and 61727-62-6 are used here. Chem., 20(3), 453-6 (English) 1977. CODEN: JMCMAR. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 27 Eleven title compds. (I): R = H,Me; R1 = H, Me, cyclopropylmethyl, cyclobutylmethyl, cyclopropylethyl, allyl) were prepd. from 6-hydroxytropinone [5932-53-6] by ketalization, Pfitzner-Moffit oxidn., Grignard reaction with p-methoxyphenyl bromide [104-92-7], dehydration, hydrogenation, treatment with methylidene or ethylidene triphenyphosphorane, and cyclization with HBr, followed by N-demethylation, N-acylation, and redn. All the compds. were fairly toxic in relation to their weak analgesic properties. I(R = H, R1 = cyclopropylmethyl) [61727-63-7] and I(R = Me, R1 = cyclopropylmethyl) [61727-64-8] had narcotic antagonist properties considerably greater than pentazocine and approx. equiv. to nalorphine. Structure-activity relations and the correlation of analgesic and narcotic antagonist properties in series of compd. derivs. are discussed. .
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