Reference

Preparation of phosphatidylserine derivatives

Preparation of phosphatidylserine derivatives. Ono, Mitsunori; Mori, Hideto (Fuji Photo Film Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 03204889 A2 6 Sep 1991 Heisei, 11 pp. (Japan).Some commonly used reagents like 139138-83-3 and 59524-02-6 are used in this experiment. CODEN: JKXXAF. CLASS: ICM: C07F009-12. APPLICATION: JP 90-137887 28 May 1990. PRIORITY: JP 89-276525 24 Oct 1989; JP 89-278013 25 Oct 1989; JP 89-278014 25 Oct 1989. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 33 The title compds. (I; R = protecting group; R1 = C8-24 linear or branched alkyl, etc.), useful as surface modifiers for lipid membrane (no data), are prepd. A soln. of PhOP(O)Cl2 in THF was added to a soln. of (S)-II (prepn. given) and N-methylimidazole in THF with stirring at room temp., followed by (S)-2,3-di-O-hexadecylglycerol (prepn. given) and N-methylimidazole in THF, to give 56.3% I (R = Me3CO2C, R1 = hexadecyl). .