Products Categories
| CAS No.: | 59703-00-3 |
|---|---|
| Name: | 4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride |
| Article Data: | 8 |
| Molecular Structure: | |
|
|
|
| Formula: | C7H9ClN2O3 |
| Molecular Weight: | 204.613 |
| Synonyms: | 4-ethyl-2,3-dioxopiperazin-1-carbonylchlorid; |
| EINECS: | 261-867-0 |
| Density: | 1.408 g/cm3 |
| Melting Point: | 100 °C |
| Boiling Point: | 292.9 °C at 760 mmHg |
| Flash Point: | 131 °C |
| Solubility: | decomposes |
| Appearance: | White to tan powder, partially agglomerated |
| Hazard Symbols: |
 C
|
| Risk Codes: | 34 |
| Safety: | 45-36/37/39-26 |
| PSA: | 57.69000 |
| LogP: | -0.08830 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 717878-06-31-(4-fluorophenyl)-4-nitro-1H-imidazole
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 32315-10-9
bis(trichloromethyl) carbonate
- 59702-31-7
1-ethyl-2,3-dioxo-piperazine
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
| Conditions | Yield |
|---|---|
| With pyridine; dmap; chloro-trimethyl-silane In dichloromethane at -25 - -20℃; | 94.3% |
| With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 10 - 20℃; for 1.06667h; Temperature; Reagent/catalyst; Green chemistry; | 93.9% |
| Stage #1: 1-ethyl-2,3-dioxo-piperazine With chloro-trimethyl-silane; triethylamine In dichloromethane at 0 - 20℃; for 1h; Inert atmosphere; Schlenk technique; Stage #2: bis(trichloromethyl) carbonate In dichloromethane at -30℃; Inert atmosphere; Schlenk technique; |
- 75-44-5
phosgene
- 59702-31-7
1-ethyl-2,3-dioxo-piperazine
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
| Conditions | Yield |
|---|---|
| With chloro-trimethyl-silane; triethylamine In tetrahydrofuran; 1,4-dioxane |
- 149-30-4
2-Mercaptobenzothiazole
A
- 120600-74-0
S-2-benzothiazolyl-4-ethyl-2,3-dioxo-1-piperazinethio-carboxylate
B
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
| Conditions | Yield |
|---|---|
| With triethylamine In dichloromethane |
- 69-53-4
ampicillin
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- 61477-96-1, 64131-97-1
piperacillin
| Conditions | Yield |
|---|---|
| With calcium carbonate In dichloromethane; water; ethyl acetate at 30 - 35℃; for 0.833333h; | 93.7% |
| With sodium acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane; water; ethyl acetate at 5 - 10℃; for 0.916667h; pH=6.5 - 7.5; Temperature; Reagent/catalyst; Green chemistry; | 92.8% |
| With triethylamine In water; ethyl acetate at 15 - 20℃; for 1h; pH=7.1; | 123.5 g |
- 72292-40-1, 72345-50-7, 72377-68-5
7β-<(2R)-2-phenyl-2-amino>acetylamino-1-carba-1-dethia-3-cephem-4-carboxylic acid
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- 72292-42-3, 72401-86-6
7β-<(2R)-2-phenyl-2-(4-ethyl-2,3-dioxopiperazine-1-yl-carbonyl)amino>acetylamino-1-carba-1-dethia-3-cephem-4-carboxylic acid
| Conditions | Yield |
|---|---|
| 93% |
- 3228-02-2
3-Methyl-4-isopropylphenol
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
| Conditions | Yield |
|---|---|
| With triethylamine In acetonitrile at 20℃; for 4h; | 92% |
| Conditions | Yield |
|---|---|
| With sodium carbonate In water at 20℃; for 11h; Reagent/catalyst; Solvent; Large scale; | 90.2% |
- 73910-33-5
7β-<(2R)-2-phenyl-2-amino>acetylamino-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- 73910-34-6
7β-<(2R)-2-phenyl-2-(4-ethyl-2,3-dioxopiperazin-1-yl-carbonyl)amino>acetylamino-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl-1-carba-1-dethia-3-cephem-4-carboxylic acid
| Conditions | Yield |
|---|---|
| With benzenesulfonamide; methyloxirane In acetonitrile for 0.416667h; | 90% |
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
| Conditions | Yield |
|---|---|
| In dichloromethane at -5 - 25℃; for 8.67h; Solvent; | 84% |
- 22818-40-2
D-4-hydroxyphenylglycine
- 59703-00-3
4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- 62893-24-7
(R)-<<(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl>amino>(4-hydroxyphenyl)acetic acid
| Conditions | Yield |
|---|---|
| With sodium carbonate; zinc dibromide In water at 200℃; for 3h; Temperature; Reagent/catalyst; Autoclave; | 83.5% |
What can I do for you?
Get Best Price
Chemistry
IUPAC Name: 4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
Molecular Formula:C7H9ClN2O3
Molecular Weight:204.610960 g/mol
Appearance:white crystal
Melting Point:100 °C
Water Solubility:decomposes
CAS DataBase Reference:59703-00-3(CAS DataBase Reference)
Synonyms of 4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBONYLCHLORIDE(59703-00-3):
edpc;1-CHLOROCARBONYL-4-ETHYL-2,3-DIOXOPIPERAZINE;4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBONYL CHLORIDE;4-ETHYL-2,3-DIOXO-PIPERAZINE-1-CARBONYL CHLORIDE;4-ETHYL-2,3-DIOXO-PIPERAZINE CARBONYL CHLORIDE;N-Ethyl-2,3-dioxypiperazine-1-carbonylchloride;N-Ethyl-2,3-dioxo-1-piperazinecarbonyl chloride;4-Ethyl-2,3-dioxo-1-piperazine carbonyl chlorides
Categories of 4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBONYLCHLORIDE(59703-00-3):
Piperaizine;Piperazine derivates;Cefoperazone
Uses
4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBONYLCHLORIDE(59703-00-3) is an important pharmaceutical intermediate mainly used for synthesis of Piperacillin and cefoperazone, etc.
Safety Profile
Safety Information of 4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBONYLCHLORIDE(59703-00-3):
Hazard Codes:C 
Risk Statements:34
34:Causes burns
Safety Statements:45-36/37/39-26
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice