Detail of "60-79-7"

CAS Number:
60-79-7
Name:
Ergoline-8-carboxamide,9,10-didehydro-N-[(1S)-2-hydroxy-1-methylethyl]-6-methyl-, (8b)-
Superlist Name:
Ergonovine
Molecular Structure:
Formula:
C₁₉H₂₃N₃O₂
Molecular Weight:
325.45
Deleted CAS:
78207-83-7|11002-48-5
Synonyms:
Ergoline-8b-carboxamide,9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methyl- (8CI);Lysergamide,N-[(S)-2-hydroxy-1-methylethyl]- (6CI);D-Lysergic acid-L-propanolamide;9,10-Didehydro-N-(alpha-(hydroxymethyl)ethyl)-6-methylergoline-8-beta-carboxamide;L-Lysergic-L(beta-hydroxyisopropylamide);9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8beta(S)-carboxamide;N-(1-(Hydroxymethyl)ethyl)-D-lysergamide;N-(2-Hydroxy-1-methylethyl)-D(+)-lysergamide;Ergobasine;D-Lysergic acid 1-hydroxymethylethylamide;Secacornin;(8β)-N-[(2S)-1-Hydroxypropan-2-yl]-6-methyl-9,10-didehydroergoline-8-carboxamide;
EINECS:
200-485-0
Density:
1.3 g/cm³
Boiling Point:
635.2 °C at 760 mmHg
Flash Point:
337.9 °C
Appearance:
solid
Hazard Symbols:
T
Risk Codes:
23/24/25
Safety:
36/37/39-45 Details

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Semicontinuous cultivation of immobilized Claviceps purpurea: Semicontinuous cultivation of immobilized Claviceps purpurea. Kopp, Bettina; Rehm, H. J. (Inst. Mikrobiol., Univ. Muenster, Muenster D-4400, Fed.Chemicals with cas numbers 548-43-6 and 2390-99-0 also play role. Rep. Ger.). Appl. Microbiol. Biotechnol., 19(3), 141-5 (English) 1984. CODEN: AMBIDG. DOCUMENT TYPE: Journal CA Section: 16 (Fermentation and Bioindustrial Chemistry) Mycelia of C. purpurea CBS 164.59 were immobilized in 2%, 4%, and 8% Ca alginate. Alkaloid prodn. by free cells declined after 60 days, whereas immobilized cells retained their activity for 200 days. The cumulative alkaloid prodn. for all fermn. cycles with 8% Ca alginate-immobilized mycelia was 25-fold higher than that from free cells. The best yields of the ergopeptide ergometrine [60-79-7] were reached with 4% gel-immobilized mycelia, whereas higher gel concns. caused a shift in the alkaloid biosynthesis towards high clavine alkaloid prodn. Beginning with the 3rd cycle of reincubation, the immobilized mycelia showed a marked tendency to fragmentize into vacuolated arthrosporoid structures and produced violet-black pigments, so that the beads recalled sclerotial structures of parasitically living Claviceps. .

The effect of oxytocics on the human cervix during midtrimester pregnancy: The effect of oxytocics on the human cervix during midtrimester pregnancy. Mackenzie, I. Z. (Nuffield Dep. Obstet.Chemicals with cas numbers 50-56-6 and 363-24-6 also play role. Gynaecol., John Radcliffe Hosp., Headington/Oxford, Engl.). Br. J. Obstet. Gynaecol., 83(10), 780-5 (English) 1976. CODEN: BJOGAS. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Section cross-reference(s): 1 In patients admitted to a hospital for 2nd trimetester therapeutic abortion, PGE2 (I) [363-24-6], PGF2.alpha. [551-11-1], and oxytocin [50-56-6] had similar but no specific effects upon the intracervical canal pressure, whereas ergometrine [60-79-7] contracted the cervix. The results are discussed in relation to cervical rupture and cervico-vaginal fistulae that have been reported following 2nd trimester abortion induced with prostaglandins. .