Reference

Therapeutic compositions containing methaqualone

Therapeutic compositions containing methaqualone. Buehler, John D.; Chemburkar, Pramod B.; Joslin, Robert S. (Rorer, William H., Inc., USA). U.S. US 4054658 18 Oct 1977, 7 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-505. NCL: 424251000. APPLICATION: US 70-43976 5 Jun 1970. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Orally administrable, rapidly sol., and readily absorbable sedative hypnotic compns. comprise methaqualone (I) [72-44-6] or its acid addn. salts contg. solubilizing adjuncts. Thus, I 150 g and glycine-HCl [6000-43-7] 150 g are intimately mixed and filled into gelatin capsules.

Effects of hydrochlorides of amino acids in test meals on gastric emptying

Effects of hydrochlorides of amino acids in test meals on gastric emptying. Fisher, M.; Hunt, J. N. (Dep. Physiol., Guy's Hosp. Med. Sch., London, Engl.). Digestion, 16(1-2), 18-22 (English) 1977. CODEN: DIGEBW. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Section cross-reference(s): 1 Four subjects were given test meals contg. various concns. of the hydrochlorides of glycine [6000-43-7], alanine [6003-05-0], arginine [1119-34-2], phenylalanine [17585-69-2], tryptophan [6159-33-7]. The gastric contents were recovered after 20 min. The vol. of the original meal recovered was assessed from the amt. of marker substance aspirated. The retardation of gastric emptying by amino acid hydrochlorides was consistent with their action as weak acids. However, tryptophan and phenylalanine were slightly more effective than predicted on the basis of their actions as acids.