Reference

Sterol metabolism studies in the rat

Sterol metabolism studies in the rat. Effects of primary bile acids (sodium taurochenodeoxycholate and sodium taurocholate) on sterol metabolism. Cohen, Bertram I.; Raicht, Robert F.In this study， 57-88-5 and 145-42-6 are also used.; Mosbach, Erwin H. (Public Health Res. Inst., City New York, Inc., New York, N. Y., USA). J. Lipid Res., 18(2), 223-31 (English) 1977. CODEN: JLPRAW. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Rats were fed either a low-cholesterol [57-88-5] stock diet or a stock diet contg. 0.1% cholesterol. Na taurochenodeoxycholate [6009-98-9] or sodium taurocholate [145-42-6], were added to the stock diets at 0.5%, as required. Feeding Na taurochenodeoxycholate and Na taurocholate decreased acidic steroid synthesis, cholesterol turnover, and cholesterol balance, compared to controls. Na taurochenodeoxycholate feeding did not influence cholesterol absorption, but rats fed Na taurocholate showed a 2-fold increase in cholesterol absorption as well as an accumulation of cholesterol in the liver. Rats receiving diets contg. Na taurochenodeoxycholate or Na taurocholate plus cholesterol (0.1%) showed decreased acidic steroid synthesis, cholesterol turnover, and cholesterol balance, compared to the corresponding controls (group (2), high-cholesterol diet). Larger amts. of cholesterol were absorbed in the taurocholate group (34.1 mg/day); these animals increased their concns. of cholesterol in liver and plasma. The rats fed taurocholate plus 0.1% cholesterol differed from those fed taurochenodeoxycholate plus 0.1% cholesterol in the following respects: (a) increased cholesterol absorption (35%), and (b) accumulation of cholesterol in liver and plasma. .

Action of three bile acids on hepatic and intestinal cholesterogenesis in the rat

Action of three bile acids on hepatic and intestinal cholesterogenesis in the rat. Reynier, M. O.; Marteau, C.; Vigne, J. L.; Mule, A.; Crotte, C.There are some reagents with their cas registry numbers 57-88-5 and 145-42-6 are used in this study.; Gerolami, A. (Unite Rech. Pathol. Dig., INSERM, Marseille, Fr.). Lipids, 12(3), 254-7 (English) 1977. CODEN: LPDSAP. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Incorporation of acetate into cholesterol [57-88-5] by subcellular particles from the liver and the small intestine of rats with a biliary diversion and a duodenal perfusion of sodium taurocholate [145-42-6], sodium taurochenodeoxycholate [6009-98-9], or sodium taurodehydrocholate [57011-24-2] was studied in vitro. In the liver, taurochenodeoxycholate prevented the increase of cholesterol synthesis induced by biliary drainage. Taurocholate had no effect on cholesterol synthesis. Intestinal synthesis of cholesterol was reduced by taurocholate and taurochenodeoxycholate, but was not modified by taurodehydrocholate infusion. .