Detail of "60117-47-7"

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A convenient synthesis of 4-diarylmethyl-, 4-(a-hydroxy-a-aryl/naphthyl)methyl- and 4-(benzoyl/naphthanoyl)-1-(2H)-phthalazinones from ninhydrin

A convenient synthesis of 4-diarylmethyl-, 4-(a-hydroxy-a-aryl/naphthyl)methyl- and 4-(benzoyl/naphthanoyl)-1-(2H)-phthalazinones from ninhydrin. Kundu, Sandip Kumar; Pramanik, Animesh (Department of Chemistry, Calcutta University, Kolkata 700 009, India). Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 43B(3), 595-603 (English) 2004 National Institute of Science Communication. CODEN: IJSBDB. ISSN: 0376-4699. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Refluxing of 2,2-diaryl-1,3-indanediones in hydrazine hydrate for a brief period affords 4-diarylmethyl-1-(2H)-phthalazinones, e.g. 60117-47-7 is the cas registry number. This chemical is also mentioned in this article. I, in very high yield. A series of 4-(a-hydroxy-a-aryl/naphthyl)methyl- and 4-(benzoyl/naphthanoyl)-1-(2H)-phthalazinones also have been synthesized via ring cleavage and cyclization of 2-hydroxy-2-aryl/naphthyl-1,3-dioxoindanes in hydrazine hydrate (99%) at room temp. in very high yields. All the ninhydrin adducts, 2,2-diaryl-1,3-indanediones and 2-hydroxy-2-aryl/naphthyl-1,3-dioxoindanes are prepd. by stirring ninhydrin and the appropriate arom. hydrocarbons in acid medium. .