Detail of "60388-02-5"

CAS Number:
60388-02-5
Name:
Zinc,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-kN3,kO4)-, (T-4)-
Molecular Structure:
Formula:
C10H6 N4 O8 Zn
Molecular Weight:
375.56664
Synonyms:
Zinc,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, zinc complex; Zincdiorotate; Zinc orotate

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Drug for affecting the zinc level in cellular metabolism mechanisms: Drug for affecting the zinc level in cellular metabolism mechanisms. Nieper, Hans A. (Nadrol-Chemie-Pharma Keizer K.-G., Ger.). Ger. Offen.Some commonly used reagents like 60388-02-5 and 9001-45-0 are used in this experiment. DE 2457524 10 Jun 1976, 10 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A61K031-44. APPLICATION: DE 74-2457524 5 Dec 1974. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacodynamics) Drugs contg. zinc orotate (I) [60388-02-5] alone or as the active ingredient influence the Zn level in the mechanism of cell metab. and are effective in the treatment of diabetes and cancer. I at 90 mg/day given orally to patients with diabetes tended to normalize blood sugar within 9 days. In cancer patients 30-50 mg I activated enzymes, esp. .beta.-glucuronidase [9001-45-0], in tumor cell lysosomes, resulting in tumor regression. I also increased the blood lymphocyte count in cancer patients. .