Detail of "6051-43-0"

CAS Number:
6051-43-0
Name:
Benzoic acid,4-(aminocarbonyl)-
Superlist Name:
Terephthalic acid monoamide
Molecular Structure:
Formula:
C₈H₇NO₃
Molecular Weight:
165.15
Synonyms:
Terephthalamicacid (6CI,7CI,8CI);4-(Aminocarbonyl)benzoic acid;4-Carbamoylbenzoic acid;p-Carbamoylbenzoic acid;p-Carboxybenzamide;
Density:
1.368g/cm³
Melting Point:
248 °C
Boiling Point:
400.5 °C at 760 mmHg
Flash Point:
196 °C
Risk Codes:
36/37/38
Safety:
26-36/37/39 Details

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Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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Controlled-release drug device and process for catalyzing the erosion of an acid labile polymer: Controlled-release drug device and process for catalyzing the erosion of an acid labile polymer. Himmelstein, Kenneth J.; Pogany, Stefano A.; Ringeisen, Cheryl; Zentner, Gaylen M. (Merck and Co., Inc. , USA). Eur. Pat. Appl. EP 208617 A1 14 Jan 1987, 15 pp. DESIGNATED STATES: R: CH, DE, FR, GB, IT, LI, NL. (European Patent Organization) CODEN: EPXXDW. CLASS: ICM: A61K009-22. ICS: A61K047-00.Several reagents with their cas registry numbers 27176-87-0 and 6051-43-0 are used here. APPLICATION: EP 86-401501 4 Jul 1986. PRIORITY: US 85-752436 8 Jul 1985. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A controlled-release device for the delivery of drugs comprises on acid-labile polymer and at least one org. acid, as an erosion catalyst, selected from the group consisting of carboxylic acids, sulfonic acids, phosphatidic acids, acidic phosphate esters, and their mixts. DETOSU-1,6-hexanediol/trans-cyclohexanedimethanol copolymer 960.0 mg was mixed with 40.0 mg N-dodecyl phthalamic acid, heated to 120-130°, and made into disks. Each disk (1 cm diam., 3 mm thick) was placed in 200 mL phosphate buffer and one of the polymer's degrdn. products, 1,6-hexanediol, was detd. by gas chromatog. The disks eroded at a zero-order rate of 3.52%/h with a lag time of 1.9 h. The polymer mixt. contg. no acidic catalyst did not measurably erode over the same time course. .

Terephthalic acid: Terephthalic acid. Wynkoop, Raymond; Hancock, Allen W. 6051-43-0 is just another one chemical used in this study., II (Suntech, Inc., USA). U.S. US 4086270 25 Apr 1978, 7 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: C07C051-08. NCL: 260515000P. APPLICATION: US 76-733617 18 Oct 1976.Some chemicals with cas registry numbers like 6051-43-0 are also used. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Terephthalonitrile was converted to the title acid in a distn. reactor system with good NH3 removal; aq. equil. hydrolysis solns. of the nitrile were introduced into a reactive distn. column at 200-60° at autogenous pressure, NH3 and water vapor were removed from the top of the column, and the bottoms product was subjected to further hydrolysis and distn. ..