CAS No.606-83-7,Benzenepropanoic acid, b-phenyl- Suppliers

Detail of "606-83-7"

CAS Number:

606-83-7

Name:

Benzenepropanoic acid, b-phenyl-

Superlist Name:

3,3-Diphenylpropionic acid

Molecular Structure:

Formula:

C₁₅H₁₄O₂

Molecular Weight:

226.27

Synonyms:

Propionicacid, 3,3-diphenyl- (6CI,7CI,8CI);Diphenylpropionic acid;NSC 631492;NSC 6797;b-Phenylbenzenepropanoic acid;

EINECS:

210-125-4

Density:

1.147 g/cm³

Melting Point:

151-154 °C(lit.)

Boiling Point:

358.3 °C at 760 mmHg

Flash Point:

255.3 °C

Solubility:

slightly soluble in water

Appearance:

white to light yellow crystalline powder

Hazard Symbols:

Risk Codes:

36/37/38

Safety:

22-24/25-37/39-26 Details

Reference

Disposition of aprophen in rats: Aarbakke, Jarle; Miura, George A.; Brown, Nesbitt D.; Gray, Richard R.; Gordon, Richard K.; Doctor, B. P.; Chiang, Peter K. (Div. Appl. Biochem., Walter Reed Army Inst. Res., Washington, DC 20307-5100, USA). J. Pharm. Pharmacol., 38(12), 928-30 (English) 1986. CODEN: JPPMAB. ISSN: 0022-3573. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The pharmacokinetics of 14C-labeled aprophen [3563-01-7] and its distribution were detd. after i. 100-37-8 and 3563-01-7 are also in the experiment.v. administration to rats. The drug was distributed rapidly with a half-life (a) of 4 min to highly perfused organs such as the brain, kidney, and adrenals. An elimination phase was apparent 10 min after injection, with a half-life (b) of 23.5 min. The high plasma clearance of the drug was due both to a large vol. of distribution and to a high metabolic rate. Aprophen could be hydrolyzed to diphenylpropionic acid [606-83-7] and diethylaminoethanol [100-37-8] in vivo and in vitro. Diethylaminoethanol competed with [3H]QNB binding to muscarinic receptors of N4TG1 cells, whereas diphenylpropionic acid did not. The lower plasma concns. and lower binding activity of diethylaminoethanol than of aprophen indicate that unchanged aprophen is largely responsible for the in vivo actions. .

Detail of "606-83-7"

Benzenepropanoic acid, b-phenyl-

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CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

CAS No.606-83-7 3,3-Diphenylpropionic acid

Reference