Detail of "607-71-6"

Reference

Importance of phospholipid methylation in liver microsomes in the sequential reactions of the induction process by 4-methylcoumarin

Importance of phospholipid methylation in liver microsomes in the sequential reactions of the induction process by 4-methylcoumarin. Feuer, G.; Belina, H.; Farkas, R.; De la Iglesia, F. A. (Dep. Clin. Biochem., Univ. Toronto, Toronto, Ont., Can.). Proc. Eur. Soc. Toxicol., 17(Predict. Chronic Toxic. Short Term Stud., Proc. Meet., 1975), 323-35 (English) 1976. CODEN: PESTD5. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Studies on the effects of coumarin [91-64-5] and 4-methylcoumarin (I) [607-71-6] on rat liver microsomes indicated the importance of Me group in the proliferation of endoplasmic reticulum membranes and in the induction of drug-metabolizing enzymes.In this experiment, several chemicals are used like 91-64-5 and 607-71-6 I served as a Me donor for the synthesis of microsomal phospholipids. The proliferation of smooth endoplasmic reticulum may be manifest through the direct or indirect action of drugs on the synthesis of methylated phospholipids, indicating the importance of this effect in the induction of drug-metabolizing enzymes. .

Designing a catalytic synthesis of 4-methylcoumarin from ortho-iodophenyl 3-butenoate: ring closure and isomerization control

Designing a catalytic synthesis of 4-methylcoumarin from ortho-iodophenyl 3-butenoate: ring closure and isomerization control. Catellani, Marta; Chiusoli, Gian Paolo; Marzolini, Giovanna; Rossi, Emanuela (Dipartimento di Chimica Organica e Industriale dell'Universita, Viale delle Scienze, Parma I-43100, Italy). Journal of Organometallic Chemistry, 525(1-2), 65-69 (English) 1996 Elsevier. CODEN: JORCAI. ISSN: 0022-328X. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) The palladium-catalyzed ring closure of o-iodophenyl 3-butenoate to 4-methylcoumarin is in competition with the isomerization to the 2-butenoic ester; the latter reaction has been controlled by the appropriate use of ligands, solvents and neutralizing agents to the point that quant. 607-71-6 and 625-35-4 are also in the experiment. yields of the cyclic compd. have been attained. .