Reference

Comparative assays according to DAB 7 and Ph Eur

Comparative assays according to DAB 7 and Ph Eur. 2. Alkaloids and analogous nitrogen compounds. Otto, Hans Hartwig; Rossbach, Dieter; Rohde, Guenter (Inst. Pharm. Chem. 551-36-0 and 6027-28-7 are cas registry numbers. These chemicals are also mentioned in this article., Univ. Marburg/Lahn, Marburg, Ger.). Dtsch. Apoth.-Ztg., 117(12), 418-21 (German) 1977. CODEN: DAZEA2. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Anal. of papaverine-HCl (I-HCl) [61-25-6], pilocarpine-HCl [54-71-7], procaine-HCl [51-05-8], tetracaine-HCl [136-47-0] and hydrochlorides of 6 other org. bases by the 2-phase titrn. described in German Pharmacopeia 7 (DAB7) and by the nonaq. titrn. described in the European pharmacopeia showed that the former method was more widely applicable than the second. The latter method is practical only for substances contg. only one basic N per mol. The degree of accuracy is comparable for both methods. .

Failure of papaverine to alter L-dopa-influenced GH and PRL secretion

Failure of papaverine to alter L-dopa-influenced GH and PRL secretion. Cooper, David S.; Jacobs, Laurence S. (Dep. 9002-62-4 and 9002-72-6 are also occured in this study. Med., Washington Univ., St. Louis, Mo., USA). J. Clin. Endocrinol. Metab., 44(3), 585-7 (English) 1977. CODEN: JCEMAZ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 13 Papaverine-HCl (I-HCl) [61-25-6] (150 mg twice a day for 2 weeks), a dose which produced marked clin. impairment in Parkinsonian patients taking L-dopa [59-92-7], failed to alter L-dopa-stimulated growth hormone [9002-72-6] secretion or L-dopa-inhibited prolactin [9002-62-4] secretion in normal volunteers. Failure to demonstrate an inhibitory effect of I on dopaminergic hypothalamic-pituitary systems, despite its inhibition of striatal dopaminergic pathways, may imply qual. or quant. functional differences between hypothalamic and striatal dopaminergic systems. .