Detail of > 61301-33-5
- CAS Number:
- 61301-33-5
- Name:
Cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole,5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, (6R,7S,13aS)-
- Formula:
- C22H24O6
- Molecular Structure:
![Molecular Structure of 61301-33-5 (Cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole,5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, (6R,7S,13aS)-)](http://www.lookchem.com/300w/2010/0623/61301-33-5.jpg)
- Synonyms:
- Cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole,5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, stereoisomer;(-)-WuweizisuC;(S)-(-)-Schisandrin C;Schisandrin C;Schizandrin C;Wuweizisu C;
- Molecular Weight:
- 384.42
- Density:
- 1.232g/cm3
- Boiling Point:
- 549.2 °C at 760 mmHg
- Flash Point:
- 226.7 °C
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Reference
- Correlation between phylogeny, chemical constituents and pharmaceutical aspects of plants and applications in drug research
- Correlation between phylogeny, chemical constituents and pharmaceutical aspects of plants and applications in drug research. Part I. (Chinese Academy of Medical Sciences; Lab. Med. Plants, Inst. Mater. Med., Peking, Peop. R. China). Chih Wu Hsueh Pao, 19(3), 172-81 (Chinese) 1977. CODEN: CHWHAY. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11, 25, 26, 28 The pharmacol. properties and chem. constituents of 9 Artemisia, 14 Salvia, 8 Schizandra, 9 Dioscorea, 9 Paeonia and 6 Pueraria species were investigated and their clin. application explored. E.g., Salvia contg. tanshinones and cryptotanshinone [35825-57-1] are antimicrobial, Schizandra contg. wuweizisu C [61301-33-5], g-schizandrin [61281-37-6], wuweizichun B [61281-39-8], schizandrin [552-66-9] and deoxyschizandrin [61281-38-7] show blood serum transaminase-lowering activity, and Pueraria contg. daidzein [486-66-8], daidzin [552-66-9], and puerarin [3681-99-0] are capable of stimulating blood circulation.
- Pharmacological studies on schizandra fruits
- Pharmacological studies on schizandra fruits. III. Effects of wuweizisu C, a lignan component of schizandra fruits, on experimental liver injuries in rats. Takeda, Shigefumi; Funo, Shyuji; Iizuka, Akira; Kase, Yoshio; Arai, Ichiro; Ohkura, Yasufumi; Sudo, Kazuhiko; Kiuchi, Noriko; Yoshida, Chizuru; et al. (Tsumura Res. Inst. Pharmacol. 300-11, Japan). Nippon Yakurigaku Zasshi, 85(3), 193-208 (Japanese) 1985. CODEN: NYKZAU. ISSN: 0015-5691. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Wuweizisu C (I) [61301-33-5] dose-dependently reduced the CCl4-induced elevation of serum transaminase activity and histol. changes such as fatty degeneration, cell necrosis, inflammatory cell infiltration. A low dose of I lowered the rise of serum transaminase activity. Uridine markedly repaired the serum-biochem. and pathol. changes. I dose-dependently inhibited fatty degeneration and decrease of serum triglyceride induced by ethionine. Thus, I may prevent hepatocellular necrosis, fatty degeneration, and inflammatory cell infiltration.
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