CAS No.614-80-2,2-Acetamidophenol Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	614-80-2
Name:	2-Acetamidophenol
Article Data:	162

Formula:	C₈H₉NO₂
Molecular Weight:	151.165
Synonyms:	o-Acetamidophenol;o-(Acetylamino)phenol;2-(Acetylamino)phenol;2-Acetaminophenol;o-Hydroxyacetanilide;Acet-o-aminofenol;N-Acetyl-o-aminophenol;N-Acetyl-2-aminophenol;Acetanilide, 2-hydroxy-;Phenol, 2-acetamido-;N-(2-hydroxyphenyl)acetamide;2'-hydroxyacetanilide;Acetamide, N- (2-hydroxyphenyl)-;
EINECS:	210-396-9
Density:	1.249 g/cm³
Melting Point:	205-210 °C(lit.)
Boiling Point:	343.1 °C at 760 mmHg
Flash Point:	161.3 °C
Appearance:	light brown powder
Hazard Symbols:	Xn, Xi
Risk Codes:	36/38-22-36/37/38
Safety:	26-36-37/39
Transport Information:	UN 2811
PSA:	49.33000
LogP:	1.42360

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Chemistry

The molecular formula of 2′-HYDROXYACETANILIDE(614-80-2) is C₈H₉NO₂and its formula weight is 151.16 g/mol. Its EINECS is 210-396-9.It has a melting point of 207-210 ^oC.2′-HYDROXYACETANILIDE(614-80-2) has the property of being dissolved in hot water and other solvents,for example alcohol.The appearance of 2′-HYDROXYACETANILIDE(614-80-2) is light brown powder. It is incompatible with strong oxidizing agents,chloroformates, acids, acid chlorides, acid anhydrides.The product Categories is Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Anilines, Amides & Amines;Phenols;Amines and Aromatics.
The chemical synonyms of are O-HYDROXYACETANILIDE;O-ACETAMIDOPHENOL;O-ACETAMINOPHENOL;N-(2-Hydroxyphenyl)acetamide;AKOS BBB/377;2-ACETYLAMINOPHENOL;2-ACETAMIDOPHENOL;2-ACETAMINO PHENOL .The molecular structure of 2′-HYDROXYACETANILIDE(614-80-2) is

Uses

2′-HYDROXYACETANILIDE(614-80-2) can be used in organic synthesis, the pharmaceutical industry (anti-tumor drug pyrimidine intermediates of benzene mustard), also be used as a hydrogen peroxide stabilizer.

Production

O-amino phenol, acetic acid and acetic anhydride mix (untill the crystallization occurs), and then the mixture is heated directly on the fire untill all dissolved, stop heating.The mixture was cooling, washed with water,and filtered.The product is derived by recrystallized from ethano at 70 ~ 80 ℃ .

Toxicity Data With Reference

1.		eye-rbt 500 mg/24H MLD		28ZPAK Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,106.
2.		orl-rat LD50:4960 mg/kg		28ZPAK Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,106.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Mildly toxic by ingestion. An eye irritant. When heated to decomposition it emits toxic fumes of NO_x. Safety 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
37/39: Wear suitable gloves and eye/face protection.Risk Codes is R22;R36/38.Hazard class is 6.1(b). Hazard Symbols: .