Detail of "6164-79-0"

Reference

Partial chemical characterization of urinary signaling pheromone in tree shrews (Tupaia belangeri)

Partial chemical characterization of urinary signaling pheromone in tree shrews (Tupaia belangeri). Von Stralendorff, F. (Dep. Anim. Physiol., Univ.In this study，6164-79-0 is also used. Bayreuth, Bayreuth D-8580, Fed. Rep. Ger.). J. Chem. Ecol., 13(3), 655-79 (English) 1987. CODEN: JCECD8. ISSN: 0098-0331. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Tree shrews of both sexes exhibit marking behavior (chinning) in response to scent marks made by the urine of fertile male conspecifics. To isolate the effective odor components, the urine was fractionated by liq.-liq. extn. and TLC, and the fractions were tested by bioassay. The results show that chinning is elicited by several lipophilic urine fractions, which are more effective in combination than alone. To characterize the complex scent signal, the lipophilic exts. from urine of the 2 sexes were analyzed by GC-MS and compared. The GC profile of the males is distinguished by pyrazine compds. not detected in the profile of the females. The profiles of the sexes also differ with regard to several volatile monocarboxylic acids, which are present at higher concns. in male than in female urine. More than 30 urine components were identified. Synthetic equiv. of these urine components were bioassayed for effectiveness in eliciting chinning and compared with one another as well as with scent substances not normally present in tree-shrew urine. Strong chinning responses were elicited by certain pyrazine compds. and some monocarboxylic acids, when presented at the high concns. specific to male urine. Marking behavior is usually not elicited by scent substances not contained in tree-shrew urine or by urine components common to mammals in general. Eviently, the male-specific scent signal of tree shrews is based less on a single unique component than on the qual. and quant. characteristics of a multicomponent mixt. In the bioassay, tree shrews of both sexes respond equally to the male specific substances by chinning. As the scent signal represented by these substances has a different meaning to males and females (rival or potential mate, resp.), chinning probably serves several different functions. .

Pyrazinyldithiolethiones

Pyrazinyldithiolethiones. Barreau, Michel; Cotrel, Claude; Jeanmart, Claude (Rhone-Poulenc S.Several substances are used for example 41110-34-3 and 6164-79-0 which are their cas registry numbers. A., Fr.). Ger. Offen. DE 2627211 30 Dec 1976, 21 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07D409-04. PRIORITY: FR 75-19408 20 Jun 1975. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Pyrazines I (R = H, Me, MeO; R1 = R2 = H, Me; X = O, S, NOH), useful as amebicides and schistosomacides, are prepd. by treatment of .beta.-oxopyrazinepropionates with P2S5 or cyclization of 3,3-bis(methylthio)-1-(pyrazinyl)-2-propen-1-ones. Thus, reaction of 97 g Et .beta.-oxopyrazinepropionate with 122 g P5S5 in pyridine gives after 1 h at reflux and work-up 15.3 g I (R = R1 = R2 = H, X = S) (II). II is active against Schistosoma mansoni in mice if given s.c. for 5 days at a rate of 125-250 mg/kg per day. .