Detail of > 62-23-7
- CAS Number:
- 62-23-7
- Name:
p-Nitrobenzoic acid
- Formula:
- C7H5NO4
- Molecular Structure:

- Synonyms:
- Benzoicacid, p-nitro- (8CI);4-Nitrobenzoic acid;Nitrodracylic acid;p-Carboxynitrobenzene;p-Nitrobenzenecarboxylic acid;
- Molecular Weight:
- 167.12
- EINECS:
- 200-526-2
- Density:
- 1.468 g/cm3
- Melting Point:
- 237-240 °C(lit.)
- Boiling Point:
- 359.1 °C at 760 mmHg
- Flash Point:
- 166.5 °C
- Solubility:
- <0.1 g/100 mL at 26 °C in water
- Appearance:
- light yellow crystalline powder
- Hazard Symbols:
Xn- Risk Codes:
- 22-41
- Safety:
- 26-39-24/25Details
- particular:
- particular
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Reference
- Heat-storage media
- Heat-storage media. (Hitachi, Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 58204085 A2 28 Nov 1983 Showa, 4 pp.Some commonly used reagents like 87-66-1 and 110-17-8 are used in this experiment. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C09K005-06. APPLICATION: JP 82-84729 21 May 1982. DOCUMENT TYPE: Patent CA Section: 52 (Electrochemical, Radiational, and Thermal Energy Technology) The title media consist of 100 parts Al(NH4)(SO4)2.12H2O and 0.1 part org. nucleating agent from the group of picric acid [88-89-1], trinitroaniline [26952-42-1], phthalic anhydride [85-44-9], fumaric acid [110-17-8], salicylic acid [69-72-7], cyanuric acid [108-80-5], succinic anhydride [108-30-5], o-chlorobenzoic acid [118-91-2] dulcitol [608-66-2], 3,5-dinitrobenzoic acid [99-34-3], melamine [108-78-1], oxamide [471-46-5], p-hydroxybenzoic acid [99-96-7], thianthrene [92-85-3], p-nitrobenzoic acid [62-23-7], and pyrogallic acid [87-66-1]. The media are used at 20-105°. .
- Metabolism of nitrotoluenes by freshly isolated Fischer 344 rat hepatocytes
- Metabolism of nitrotoluenes by freshly isolated Fischer 344 rat hepatocytes. DeBethizy, J. Don; Rickert, Douglas E. (Dep. Gen. Biochem. Toxicol., Chem. Ind. Inst. Toxicol., Research Triangle Park, NC 27709, USA). Drug Metab. Dispos., 12(1), 45-50 (English) 1984. CODEN: DMDSAI. ISSN: 0090-9556. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Hepatocytes were incubated with U-14C-labeled 2-nitrotoluene (I)(2NT) [88-72-2], 3-nitrotoluene (3NT) [99-08-1], or 4-nitrotoluene (4NT) [99-99-0] at concns. from 25 to 1000 mM for up to 60 min. 2NT was converted to 2-nitrobenzyl alc.In this article, certain chemicals are used. Some of their cas registry numbers are 89076-35-7 and 612-25-9 [612-25-9] (52%), 2-nitrobenzyl alc. glucuronide [89076-33-5] (28%), an unidentified metabolite (20%), and 2-nitrobenzoic acid [552-16-9] (3%). Metabolites from 3NT were 3-nitrobenzoic acid [121-92-6] (56%), 3-nitrobenzyl alc. [619-25-0] (29%), and 3-nitrobenzyl alc. glucuronide [89076-34-6] (13%). 4NT was metabolized to S-(4-nitrobenzyl)glutathione [6803-19-6] (68%), 4-nitrobenzyl alc. [619-73-8] (12%), sulfate [89090-09-5] and glucuronide [89076-35-7] conjugates of 4-nitrobenzyl alc. (6%), and 4-nitrobenzoic acid [62-23-7] (2%) (expressed as percentage of total metab.). The formation of the resp. nitrobenzyl alcs. by hepatocytes was linear with respect to time for 15-20 min. The formation of other metabolites was linear over a 45-min incubation period. Incubation of 2NT, 3NT, or 4NT (1 mM) with rat hepatic microsomes produced only the resp. nitrobenzyl alcs. and the rate of formation was linear for 90 min. Thus, each nitrotoluene isomer is metabolized to the corresponding benzyl alc., but substantial differences in the metab. of the benzyl alcs. exist. .
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