Detail of "62-32-8"

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CAS Number:
62-32-8
Name:
1,2-Benzenediol,4-[2-(methylamino)ethyl]-, hydrochloride (1:1)
Superlist Name:
N-Methyldopamine hydrochloride
Molecular Structure:
Formula:
C9H13 N O2 . Cl H
Molecular Weight:
203.69
Synonyms:
1,2-Benzenediol,4-[2-(methylamino)ethyl]-, hydrochloride (9CI); Pyrocatechol, 4-[2-(methylamino)ethyl]-,hydrochloride (8CI); 3,4-Dihydroxyphenylethylmethylamine hydrochloride;4-(2-Methylaminoethyl)-1,2-benzenediol hydrochloride;4-(2-Methylaminoethyl)pyrocatechol hydrochloride; Deoxyepinephrinehydrochloride; Ephinine hydrochloride; Epinine hydrochloride; Methyl[b-(3,4-dihydroxyphenyl)ethyl]aminehydrochloride; Methyldopamine hydrochloride; N-Methyldopamine hydrochloride
Safety:
A poison by subcutaneous and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NO_x and HCl. Details

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Pharmaceutical compositions containing epinine or a pharmaceutically acceptable salt thereof and their therapeutic use: Pharmaceutical compositions containing epinine or a pharmaceutically acceptable salt thereof and their therapeutic use. Casagrande, Cesare; Ghirardi, Paolo; Goldberg, Leon Isadore; Marchetti, Germano (SIMES Societa Italiana Medicinali e Sintetici S.p.A., Italy). Eur. Pat. Appl. EP 132880 A1 13 Feb 1985, 11 pp. DESIGNATED STATES: R: BE, CH, DE, FR, GB, IT, LI, LU, NL, SE. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: A61K031-135. ICS: A61K009-22; A61K009-00. APPLICATION: EP 84-201033 12 Jul 1984. PRIORITY: IT 83-22118 19 Jul 1983. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 Pharmaceutical compns. for treatment of congestive heart failure in humans comprise epinine (I) [501-15-5] or its salt such that it allows the release of 0.5-5.0 mg I/kg/min for ~6 h. A sustained release (~6 h) tablet contained I-HCl [62-32-8] 400, PVP 12, microgranulated cellulose 100, acrylic ester methacrylic ester copolymer 20, hydrogenated castor oil 8, TiO2 4, and polyethylene glycol 1 mg. The tablets were film-coated and administered at 1-4 tablets in 24 h depending on the patient's condition and the desired effects.