Reference

Effect of sodium pentobarbital on the apparent turnover of acetylcholine in different brain regions

Effect of sodium pentobarbital on the apparent turnover of acetylcholine in different brain regions. Nordberg, Agneta; Sundwall, Anders (Biomed. Cent., Univ. Uppsala, Uppsala, Swed.). Acta Physiol. Scand., 99(3), 336-44 (English) 1977. CODEN: APSCAX. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 13 The turnover rate of acetylcholine (ACh) [51-84-3] was measured in 6 different brain regions in the mouse following pulse injection of 3H-labeled choline (Ch) [62-49-7].Some commonly used reagents like 51-84-3 and 57-33-0 are used in this experiment. The time course of the change in 3H-ACh/3H-Ch ratio was linear 0-60 sec in all brain regions after administration of 3H-Ch. Plots of the specific radioactivities of ACh and Ch vs. time indicated a precursor-product relation in all brain regions, except the cerebellum, both in control and Na pentobarbital (I) [57-33-0] anesthesized animals. The turnover was highest in the striatum (55 nmol.cntdot.g-1.cntdot.min-1), while in the cortex and hippocampus this value was approx. half (27 and 21 nmol.cntdot.g-1.cntdot.min-1). In the midbrain and medulla oblongata the turnover rates were only 11 and 10 nmol.cntdot.g-1.cntdot.min-1. I anesthesia decreased the turnover in the cortex and hippocampus to about 60 to 70%. .

Effect of various auxins on growth and production of tropane alkaloids by in vitro tissue culture of Datura metel Linn

Effect of various auxins on growth and production of tropane alkaloids by in vitro tissue culture of Datura metel Linn. Khanna, Pushpa; Khanna, Renu (Dep. Bot., Univ. Rajasthan, Jaipur, India). Indian J. Pharm., 38(5), 120-3 (English) 1976. CODEN: IJPAAO. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemicals) Supplementing modified Murashige-Skoog medium with 1 ppm naphthaleneacetic acid (I) [26445-01-2] increased the alkaloid formation by the title callus culture more than did IAA [87-51-4] or 2,4-D (II) [94-75-7]. However, II stimulated the growth more than did IAA and I. The alkaloids formed on I and IAA were atropine [51-55-8], choline [62-49-7], hyoscine [51-34-3], and hyoscyamine [101-31-5].Except for chemicals metioned above, 101-31-5 and 51-55-8 are also used. .