Detail of "620-20-2"

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CAS Number:
620-20-2
Name:
Benzene,1-chloro-3-(chloromethyl)-
Superlist Name:
3-Chlorobenzyl chloride
Molecular Structure:
Formula:
C₇H₆Cl₂
Molecular Weight:
161.03
Synonyms:
Toluene,m,a-dichloro- (8CI);1-Chloro-3-(chloromethyl)benzene;NSC 76577;m,a-Dichlorotoluene;m-Chlorobenzyl chloride;m-Chlorophenylmethyl chloride;a,3-Dichlorotoluene;a,m-Dichlorotoluene;
EINECS:
210-629-4
Density:
1.247 g/cm³
Boiling Point:
213.7 °C at 760 mmHg
Flash Point:
98.9 °C
Appearance:
Colorless to light yellow liquid
Hazard Symbols:
C, N, Xn
Risk Codes:
34-51/53-43-36-20/21/22
Safety:
26-36/37/39-45-61-14C Details
Transport Information:
UN 2235 6.1/PG 3

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Absolute rate constants for the reaction of triethylsilyl radicals with ring-substituted benzyl chlorides: Absolute rate constants for the reaction of triethylsilyl radicals with ring-substituted benzyl chlorides.Some chemicals with cas registry numbers like 24669-77-0 and 620-20-2 are also used. Chatgilialoglu, C.; Ingold, K. U.; Scaiano, J. C. (Div. Chem., Natl. Res. Counc. Canada, Ottawa, ON K1A 0R6, Can.). J. Org. Chem., 52(5), 938-40 (English) 1987. CODEN: JOCEAH. ISSN: 0022-3263. DOCUMENT TYPE: Journal CA Section: 29 (Organometallic and Organometalloidal Compounds) Section cross-reference(s): 22 Abs. rate consts. at 24 ± 2° for the reaction of Et3Si· radicals with RC6H4CH2Cl (R = 3-CF3, 4-F, 4-Me, etc.) and with R1R2C6H3CH2Cl [R1R2 = 3,5-(CF3)2, 3,5-Cl2, 3,4-Cl2] were correlated by the Hammett equation using s substituent consts., r = +0.64. .

Preparation of glutamic, aspartic, and 2-aminoadipic acid amides with antigastrin activity: Preparation of glutamic, aspartic, and 2-aminoadipic acid amides with antigastrin activity. Makovec, Francesco; Rovati, Luigi Angelo; Rovati, Claudio Lucio (Rotta Research Laboratorium S.p.A., Italy). PCT Int. Appl. WO 9210479 A1 25 Jun 1992, 46 pp. DESIGNATED STATES: W: AU, CA, JP, US; RW: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE. (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: C07D221-20. ICS: C07D217-06; C07C237-22; C07D491-10; A61K031-435; A61K031-195. 620-20-2 which is the cas registry number is also used here. ICI: C07D491-10, C07D317-00, C07D221-00. APPLICATION: WO 91-EP2342 6 Dec 1991. PRIORITY: IT 90-67995 11 Dec 1990. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1, 34 HO2C(CH2)rCH(R1CONH)COR2 (r = 1-3; R1 = substituted Ph, 2-naphthyl, (substituted) heterocyclyl; R2 = (substituted) spiroheterocyclyl, -bicyclylamino, -adamantylalkylamino) are prepd. g-Benzyl (R)-carbobenzoxyamino)-5-(8-azaspiro[4.5]decan-8-yl)-5-oxopentanoat e (prepn. given) was deprotected to the amino deriv. to which in aq. Na2CO3 was added 3-ClC6H4COCl to give azospirodecane I. Antagonism toward gastric acid secretion induced by pentagastrin of I was ID50 20 mg/kg. .