Reference

A rapid method for detection of synergic "in vitro" effect of Hill reaction inhibitor mixtures

A rapid method for detection of synergic "in vitro" effect of Hill reaction inhibitor mixtures. Kovac, J.; Henselova, Maria; Varkonda, S. (Res. Inst. Agrochem. Technol., Bratislava-Predmestie, Czech.). Photosynthetica, 12(1), 87-8 (English) 1978. CODEN: PHSYB5. ISSN: 0300-3604. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemicals) A simple method for rapid detection of the synergic effect of Hill reaction inhibitor mixts. was developed. The method was tested on the atrazine-defenuron mixt. [66536-95-6] (3:2). The acetone solns. of gradually increasing amts. of herbicide mixt. and each single component were applied to the chromatog. paper. The paper was sprayed with a homogenate of isolated chloroplasts and a soln. of 2,6-dichlorophenol indophenol-sodium salt [620-45-1]. Following light exposure the synergic effect of herbicide mixt. was evaluated by comparing the intensity of blue contrasting inhibition spots on a yellow-green background.

Separation of the strength and selectivity of the microbiological effect of synthetic dyes by spectral mapping technique

Separation of the strength and selectivity of the microbiological effect of synthetic dyes by spectral mapping technique. Oros, Gyula; Cserhati, Tibor; Forgacs, Esther (Plant Protection Institute, Hungarian Academy of Sciences, Budapest 1022, Hung.). Chemosphere, 52(1), 185-193 (English) 2003 Elsevier Science Ltd. CODEN: CMSHAF. ISSN: 0045-6535. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The growth inhibitory effect of 30 synthetic dyes on 22 bacteria (test organisms) belonging to various taxonomic groups was detd. The strength (potency) and selectivity of the biol. effect were sepd. by the spectral mapping technique, reducing the dimensionality of the selectivity maps to two by the nonlinear mapping technique. The relationship between biol. effect and physicochem. parameters of dyes was elucidated by stepwise regression anal. It has been established that the strength of the effect of anthracene and trityl derivs. was higher than that of azobenzene dyes and significantly depended on the hydrophobicity of the compd. The selectivity of the effect also depended on hydrophobicity and on the nonpolar unsatd. 581-64-6 and 620-45-1 are also in the experiment. surface area of the dyes. Gram neg. and Gram pos. bacteria differed in the strength and selectivity of their response to dyes indicating the marked impact of the taxonomical position on the response. Contrary to other multivariate math. statistical methods biol. activity may be divided by SPM into potency and selectivity values, therefore, application of the technique in future QSAR studies is highly recommended. .