Detail of "63089-86-1"

Reference

Comparison of cytotoxic effects of chemicals in four different cell types

Comparison of cytotoxic effects of chemicals in four different cell types. Sasaki, K.; Tanaka, N.; Watanabe, M.; Yamada, M. (Food Drug Saf. Cent., Hadano 257, Japan). Toxicol. in Vitro, 5(5-6), 403-6 (English) 1991. CODEN: TIVIEQ. ISSN: 0887-2333. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Cytotoxic effects were compared using a colony-formation assay in 3 established cell lines (Balb 3T3, mouse whole embryo, ARLJ301-3, rat liver and FRSK, rat keratinocytes) and one primary cell culture (RC-1, rabbit cornea) with the Draize eye irritancy score in vivo. The cells were treated with 52 chems. on the day after plating, then cultured for 7 or 8 days. The 50% inhibition dose (ID50) for each chem. was calcd. based on the colony no. With a few exceptions, the cytotoxicities of the chems. were in the following order in all 4 cells: cationic detergents > anionic detergents > nonionic detergents > glycol or oil. These results were almost the same as the data in vivo. The correlation coeffs. of the ID50 to the Draize score of 20 in vivo were 0.57 (Balb 3T3), 0. 1338-43-8 and 63089-86-1 which are cas registry numbers of chemicals are mentioned.61 (ARLJ301-3), 0.71 (FRSK) and 0.65 (RC-1). Balb 3T3 and ARLJ301-3 cells were slightly more sensitive to chems. than FRSK and RC-1 cells. These results suggest that the colony-formation assay using established cell lines is an attractive method for the screening of chems. in that large differences among cell types in their response to direct-acting chems., were not obsd. .

Deacidification of esters

Deacidification of esters. Sekine, Fumimaro; Iwahashi, Masaaki; Ukiana, Toshinao; Amo, Makoto (Kao Corp., Japan).Several substances are used for example 63089-86-1 and 1310-73-2 which are their cas registry numbers. Jpn. Kokai Tokkyo Koho JP 62004244 A2 10 Jan 1987 Showa, 3 pp. (Japan) CODEN: JKXXAF. CLASS: ICM: C07C067-60. ICS: C08G065-32; C11B003-06. APPLICATION: JP 85-141859 28 Jun 1985. DOCUMENT TYPE: Patent CA Section: 45 (Industrial Organic Chemicals, Leather, Fats, and Waxes) Section cross-reference(s): 23 Fatty acid esters, contg. free fatty acids, are deacidified by alkali metal soap formation with alkali metal carbonates, bicarbonates, or hydroxides, followed by sepn. of pptd. alk. earth metal soaps formed from the addn. of alk. earth metal halides. Emasol S-10 (100 g; sorbitan monostearate: acid value 9.4 mg KOH/g) was mixed with 3.14 g 30% aq. KOH at 80° and stirred for 30 min under N, then 4.05 g 25% aq. CaCl2 was added, the mixt. stirred at 80° for 30 min and filtered to give a clear filtrate (acid value 0.01 mg KOH/g) in 90.3% yield. .