Products Categories
CAS No.: | 6317-37-9 |
---|---|
Name: | 5-Nitrothiophene-2-carboxylic acid |
Article Data: | 35 |
Molecular Structure: | |
Formula: | C5H3NO4S |
Molecular Weight: | 173.149 |
Synonyms: | 5-Nitro-2-thienylcarboxylic acid;5-Nitro-2-thiophenecarboxylic acid;2-Carboxy-5-nitrothiophene;5-NTCA;NSC 41707; |
EINECS: | 228-654-4 |
Density: | 1.676 g/cm3 |
Melting Point: | 156-159 (Lit.)oC |
Boiling Point: | 367.2 °C at 760 mmHg |
Flash Point: | 175.9 °C |
Appearance: | Pale yellow solid |
Hazard Symbols: | Xi |
Safety: | 24/25 |
PSA: | 111.36000 |
LogP: | 1.87770 |
(5-nitrothiophen-2-yl)methanol
5-nitrothiophene-2-carboxylic acid
Conditions | Yield |
---|---|
With silica-supported Jones reagent In dichloromethane for 0.035h; | 99.7% |
Conditions | Yield |
---|---|
With bromine; sodium acetate; acetic acid | 98.5% |
With hydrogenchloride; bromine; sodium hydroxide In water | 98.2% |
With sodium hypobromide; sodium acetate; acetic acid | 92% |
2-thiophenylcarboxylic acid
A
5-nitrothiophene-2-carboxylic acid
B
4-nitro-2-thiophenecarboxylic acid
Conditions | Yield |
---|---|
With nitric acid; acetic anhydride; acetic acid at 20℃; for 4h; Nitration; | A 17% B 34% |
With sulfuric acid; nitric acid at 0 - 10℃; for 1.25h; | |
With sulfuric acid; nitric acid at 10 - 20℃; | A n/a B 18.2 g |
With sulfuric acid; nitric acid at 10 - 20℃; Overall yield = 18.2 g; |
5-nitro-2-thienyl cyanide
5-nitrothiophene-2-carboxylic acid
Conditions | Yield |
---|---|
With hydrogenchloride |
2-acetyl-5-nitrothiophene
A
5-nitrothiophene-2-carboxylic acid
Conditions | Yield |
---|---|
With nitric acid |
2-thiophenylcarboxylic acid
nitric acid
acetic anhydride
A
2-nitrothiophene
B
5-nitrothiophene-2-carboxylic acid
C
4-nitro-2-thiophenecarboxylic acid
Conditions | Yield |
---|---|
at -5℃; |
Conditions | Yield |
---|---|
With nitric acid; acetic anhydride at -5℃; |
2-thiophenecarboxaldehyde diacetate
5-nitrothiophene-2-carboxylic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: acetic acid anhydride; nitric acid; acetic acid 2: aqueous sulfuric acid 3: aqueous potassium permanganate solution; aq. NaOH solution View Scheme |
5-nitrothiophene-2-carboxaldehyde diacetate
5-nitrothiophene-2-carboxylic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aqueous sulfuric acid 2: aqueous potassium permanganate solution; aq. NaOH solution View Scheme | |
Multi-step reaction with 2 steps 1: ethanol; sulfuric acid 2: chromium (VI)-oxide; aqueous sulfuric acid / 110 °C View Scheme |
What can I do for you?
Get Best Price
IUPAC Name: 5-Nitrothiophene-2-carboxylic acid
Synonyms of 5-Nitrothiophene-2-carboxylic acid (CAS NO.6317-37-9): 5-Nitro-2-thenoic acid
CAS NO: 6317-37-9
Molecular Formula: C5H3NO4S
Molecular Weight: 173.15
Molecular Structure:
EINECS: 228-654-4
H bond acceptors: 5
H bond donors: 1
Freely Rotating Bonds: 2
Polar Surface Area: 100.36 Å2
Index of Refraction: 1.659
Molar Refractivity: 38.11 cm3
Molar Volume: 103.2 cm3
Surface Tension: 79.1 dyne/cm
Density: 1.676 g/cm3
Flash Point: 175.9 °C
Enthalpy of Vaporization: 64.74 kJ/mol
Boiling Point: 367.2 °C at 760 mmHg
Vapour Pressure: 4.88E-06 mmHg at 25°C
SMILES: O=C(O)c1sc([N+](=O)[O-])cc1
InChI: InChI=1/C5H3NO4S/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)
InChIKey: UNEPVPOHGXLUIR-UHFFFAOYAD
Std. InChI: InChI=1S/C5H3NO4S/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)
Std. InChIKey: UNEPVPOHGXLUIR-UHFFFAOYSA-N
Product Categories of 5-Nitrothiophene-2-carboxylic acid (CAS NO.6317-37-9): Heterocycles;Carboxylic Acids;Thiophenes & Benzothiophenes;Thiophene&Benzothiophene;Carboxylic Acids;Thiophenes & Benzothiophenes;Building Blocks;Heterocyclic Building Blocks;Thiophenes
Hazard Codes: Xi
WGK Germany: 3
Hazard Note: Irritant