Detail of "6325-93-5"

Reference

Photochemistry of photodynamic compounds

Photochemistry of photodynamic compounds. VII. Identification of certain products of sulfanilamide photolysis in aqueous solutions.In this study， 63-74-1 and 4320-29-0 are also used. Pawlaczyk, Jan; Turowska, Wlodzimiera (Inst. Chem. Anal., Sch. Med., Poznan, Pol.). Acta Pol. Pharm., 33(4), 505-9 (Polish) 1976. CODEN: APPHAX. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Photolysis of an 0.8% aq. soln. of sulfanilamide (I) [63-74-1] resulted in the formation of 4,4'-azobenzenesulfonamide [4320-29-0], 4-hydroxylamino- [877-67-8] and 4-nitrobenzenesulfonamide [6325-93-5], and 4 unidentified products. The mechanism of the decompn. is suggested. .

Spectroscopic studies of cutaneous photosensitizing agents

I. Spin trapping of photolysis products from sulfanilamide, 4-aminobenzoic acid, and related compounds. Chignell, Colin F.; Kalyanaraman, B.; Mason, Ronald P.; Sik, Robert H. (Lab. Environ. Biophys., Natl. Inst. Environ. Health Sci., Research Triangle Park, NC 27709, USA). Photochem. Photobiol., 32(5), 563-71 (English) 1980. CODEN: PHCBAP. ISSN: 0031-8655. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) UV photolysis of sulfanilamide [63-74-1] in aq. soln. yielded ·C6H4SO2NH2 [76890-77-2], PhSO2· [34014-44-3], ·SO2NH2 [62470-59-1], and SO3-· [12210-38-7] or SO2-· [12143-17-8], as detd. by spin trapping with 2-methyl-2-nitrosopropane. 4-Aminobenzoic acid [150-13-0] yielded ·C6H4CO2H [65312-85-8]. Both also generated aq. electrons of H atoms; this was not obsd. with 4-dimethylaminobenzoic acid [619-84-1]. Photolysis of 4-iodobenzenesulfonamide [825-86-5] and 4-nitrobenzenesulfonamide [6325-93-5] also yielded ·C6H4SO2NH2, and ·C6H4CO2H was generated from 4-nitrobenzoic acid [62-23-7] and 4-iodobenzoic acid [619-58-9]. ·C6H4NO2 [2395-99-5] was formed by 4-nitroaniline [100-01-6], 1,4-dinitrobenzene [100-25-4], and 4-iodonitrobenzene [636-98-6] irradn. The radicals generated from sulfonilamide and 4-aminobenzoic acid may play a role in the phototoxic and photoallergic response sometimes elicited by these drugs.