Reference

Synthesis of biologically active molecules by imprinting polymerization

All Rights Reserved. Synthesis of biologically active molecules by imprinting polymerization. Piletsky, S. A.; Piletska, E. V.; Sergeyeva, T. A.; Nicholls, I. A.; Weston, D.; Turner, A. P. F. (Inst. BioSci. Technol., Cranfield Univ., Silsoe/Bedfordshire MK45 4DT, UK). Biopolimeri i Klitina, 22(1), 63-67 (English) 2006 Institut Molekulyarnoi Biologii i Genetiki NAN Ukraini. CODEN: BKILAK. DOCUMENT TYPE: Journal CA Section: 35 (Chemistry of Synthetic High Polymers) Section cross-reference(s): 11 Highly crosslinked molecularly imprinted polymers (MIPs) are synthetic materials with properties mimicking those of natural receptors. The ability of MIP nanoparticles to manifest biol. activity is described. Molecularly imprinted polymers were synthesized by copolymn. 6342-17-2 and 104-98-3 which are cas registry numbers of chemicals are mentioned. of urocanic acid and N,N'-bis(acryloyl)piperazine in the presence of herbicide binding D1 protein, ground and sepd. from the template by washing and ultrafiltration. The MIP nanoparticles retained affinity to the template. Moreover, the imprinted polymers were able to activate photosystem II in thylakoid membranes. This provides the first example of the use of imprinted polymers for attenuation of a biol. system and opens new possibilities for their application in pharmacol., biotechnol., and medicine. .