Reference

Prophylactic and therapeutic use of phenobarbitone in the management of neonatal jaundice

Prophylactic and therapeutic use of phenobarbitone in the management of neonatal jaundice. Misra, P. K.; Bajpai, P. C.; Agrawal, S. S.; Upadhyay, V. K. (Dep. Pediatr., King George's Med. Coll., Lucknow, India). Indian J. Med. Res., 65(3), 409-15 (English) 1977. CODEN: IJMRAQ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) A prospective study was conducted to evaluate the role of phenobarbitone (I) [50-06-6] in the prevention and treatment of neonatal jaundice. I decreased plasma bilirubin [635-65-4] levels during prophylactic use in Coomb's neg. babies. I did not have a significant role in the treatment of established jaundice in normal or low birth wt. newborns. I was given orally in 3 divided doses of 6 mg/kg/day to normal wt. newborns and 5 mg/kg/day to low birth wt. newborns. No serious side effects were obsd.

Preliminary results of studies of the health status of workers exposed to vinyl chloride (VC)

Preliminary results of studies of the health status of workers exposed to vinyl chloride (VC). Wedrychowicz, Adam; Dura, K.; Garlinska, J.; Pabian, J.; Popiela, T.; Stachura, J.; Szybinski, Z. (Krakow, Pol.). Przegl. Lek., 33(11), 936-41 (Polish) 1976. CODEN: PRLKAV. DOCUMENT TYPE: Journal CA Section: 59 (Air Pollution and Industrial Hygiene) Section cross-reference(s): 35 Detn. of alk. phosphatase (I) [9001-78-9], alanine aminotransferase [9000-86-6], and cholinesterase [9001-08-5] activities in workers exposed to vinyl chloride (II) [75-01-4] is very important. Dilation of the liver, abnormalities in liver function, higher I activity, and lower prothrombin [9001-26-7] activity are more frequent in workers exposed to higher I concns. Slight but reproducible deviations were obsd. in liver enzyme activities and bilirubin [635-65-4] levels. Morphol. changes in the liver were obsd. at all II concns. No cases of haemangiosarcoma were diagnosed.