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63989-75-3

Basic Information
CAS No.: 63989-75-3
Name: (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one
Article Data: 2
Molecular Structure:
Molecular Structure of 63989-75-3 ((S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one)
Formula: C27H27 N O6
Molecular Weight: 461.514
Synonyms: Benzamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-;Benzo[a]heptalene, benzamide deriv.; N-Benzoyltetra-O-methylcolchicinic acid;NSC 33410
Density: 1.28g/cm3
Boiling Point: 780.3°C at 760 mmHg
Flash Point: 425.7°C
Safety: Poison by intraperitoneal and subcutaneous routes. Mutation data reported. See also COLCHICINE and ETHERS. When heated to decomposition it emits toxic fumes of NOx.
PSA: 83.09000
LogP: 4.55640
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  • Benzamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

  • Casno:

    63989-75-3

    Benzamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

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  • N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide,CAS:63989-75-3

  • Casno:

    63989-75-3

    N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide,CAS:63989-75-3

    Min.Order: 1 Kilogram

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  • Benzamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

  • Casno:

    63989-75-3

    Benzamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

    Min.Order: 1 Metric Ton

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Chemistry

Product Name: (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one  
CAS: 63989-75-3
The Molecular formula of (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one (CAS NO.63989-75-3): C27H27NO
The Molecular Weight of (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one (CAS NO.63989-75-3): 461.5064
The Molecular Structure of (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one (CAS NO.63989-75-3):  

Density: 1.28 g/cm3 
Flash Point: 425.7 °C
Boiling Point: 780.3 °C at 760 mmHg 
Index of Refraction: 1.62 
Molar Refractivity: 126.68 cm3 
Molar Volume: 360.5 cm3 
Polarizability: 50.22×10-24cm3 
Surface Tension: 55 dyne/cm 
Enthalpy of Vaporization: 113.54 kJ/mol 
Vapour Pressure: 2.71E-24 mmHg at 25°C

Toxicity Data With Reference

1.    

oms-mus-ipr 8 mg/kg

    CANCAR    Cancer. 3 (1950),130.
2.    

oms-mus-par 32 mg/kg

    CANCAR    Cancer. 3 (1950),134.
3.    

spm-mus-par 32 mg/kg

    CANCAR    Cancer. 3 (1950),134.
4.    

ipr-mus LD50:32 mg/kg

    MDREP*    U.S. Army, Chemical Corps Medical Division Reports. (Army Chemical Center, MD) No 204 ,1949.
5.    

ims-mus LD50:27,924 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 26 (1983),1365.
6.    

scu-cat LDLo:12,500 µg/kg

    AEXPBL    Archiv fuer Experimentelle Pathologie und Pharmakologie. 72 (1913),228.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Mutation data reported. See also COLCHICINE and ETHERS. When heated to decomposition it emits toxic fumes of NOx.

Specification

  (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(benzoylamino)benzo[a]heptalen-9(5H)-one with CAS number of 63989-75-3 is also called for 4-14-00-00952 (Beilstein Handbook Reference) ; BRN 3184511 ; Benzamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- ; Colchicine, N-benzoyl-N-deacetyl- ; N-Benzoyl tmca methyl ether ; N-Benzoyl trimethyl colchicinic acid methyl ether ; NBenzoyltrimethylcol chicinsaeuremethylaether .