Detail of > 64-43-7
- MSDS Download
- CAS Number:
- 64-43-7
- Name:
Amobarbital sodium
- Formula:
- C11H18N2O3·Na
- Molecular Structure:
- Synonyms:
- Barbamyl;Dorminal;Dormital;Dusotal;Hypnobal;Inmetal;Iosmytal sodium;Isomytal sodium;S. P. Amobarb;Sodium 5-ethyl-5-(3-methylbutyl)barbiturate;Sodium 5-ethyl-5-isopentylbarbiturate;Sodium Amytal;Sodium Barbamyl;Sodiumamital;Sodium amobarbital;Sodium amylobarbital;Sodium amylobarbitone;Sodiumethylisoamylbarbiturate;Sodium isoamylethylbarbiturate;Talamo;2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-(3-methylbutyl)-, sodium salt (1:1);2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-(3-methylbutyl)-, monosodium salt (9CI);Barbituric acid,5-ethyl-5-isopentyl-, sodium deriv. (7CI);Barbituric acid,5-ethyl-5-isopentyl-, sodium salt (8CI);Alitinal;Ambarlone;Amiotal;Amsebarb;Amylobarbitone sodium;5-Ethyl-5-(3-methylbutyl)-2,4,6-(1H,3H,5H)-pyrimidinetrione sodium salt;
- Molecular Weight:
- 248.29
- EINECS:
- 200-584-9
- Solubility:
- very soluble in water, soluble in ethanol, hardly soluble in diethyl ether
- Appearance:
- white powder
- Hazard Symbols:
Xn- Risk Codes:
- 22
- Safety:
- 36Details
- Transport Information:
- UN 2811 6.1/PG 3
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Reference
- Ethanol and the disposition of amylobarbitone: effect of dose and significance as a mechanism for increased toxicity
- Ethanol and the disposition of amylobarbitone: effect of dose and significance as a mechanism for increased toxicity. Tilstone, W. J.; Reavey, P. C. (Dep. Pharm. Chem., Univ. Strathclyde, Glasgow, Scot.). J. Pharm. Pharmacol., 30(5), 319-20 (English) 1978. CODEN: JPPMAB. ISSN: 0022-3573. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 4 EtOH [64-17-5] (0.8 and 3.2 g/kg, i.p.) prolonged the plasma half-life of amylobarbitone Na (I) [64-43-7] (100 mg/kg, i.p.) in rats, but only at the higher dose was this due to impaired I metab.
- Compositions with sedative-hypnogenic action
- Compositions with sedative-hypnogenic action. Florea, Taisia; Popa, Viorica; Grigorescu, Silvia; Trepcea, Lidia; Dragan, Anca; Popescu, Mariana (Intreprinderea de Medicamente, Bucuresti, Rom.). Rom. RO 83817 B 30 Apr 1984, 2 pp. (Romanian). (Romania). CODEN: RUXXA3. CLASS: IC: A61K031-515; A61K009-14. APPLICATION: RO 82-107379 28 Apr 1982. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A pharmaceutical compn. (capsules or tablets) with sedative-hypnogenic activity comprises DL-tryptophan (I) [54-12-6] 0.5-1.0 g and Na amytal (II) [64-43-7] 0.01-0.02 g, and usual excipients. The dosage for the sedative is I 0.05 g and II 0.01 g, 2-3 times daily, and for the hypnotic I 1.0 g and II 0.02 g 1-2 times daily.
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