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CAS No.: | 64019-93-8 |
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Name: | Dipivefrin hydrochloride |
Molecular Structure: | |
Formula: | C19H29 N O5 . Cl H |
Molecular Weight: | 387.904 |
Synonyms: | Propanoicacid, 2,2-dimethyl-, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester,hydrochloride (9CI); Propanoic acid, 2,2-dimethyl-,4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester, hydrochloride, (?à)-; D Epifrin; Diopine; Diphemin;Dipivefrin hydrochloride; Dipivefrine hydrochloride; Pivalephrine; Propine |
EINECS: | 264-609-5 |
Melting Point: | 158-159° |
Boiling Point: | 473.7 °C at 760 mmHg |
Flash Point: | 240.3 °C |
Safety: | Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl. |
PSA: | 84.86000 |
LogP: | 4.03530 |
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Chemical Name: Dipivefrin hydrochloride
IUPAC NAME: [2-(2,2-dimethylpropanoyloxy)-5-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride
CAS No.: 64019-93-8
EINECS: 264-609-5
Molecular Formula: C19H30ClNO5
Molecular Weight: 387.8982 g/mol
Flash Point: 240.3 °C
Boiling Point: 473.7 °C at 760 mmHg
Following is the structure of Dipivefrin hydrochloride (64019-93-8):
The chemical synonymous of Dipivefrin hydrochloride (64019-93-8) are Dipivalylepinephrinehydrochloride ; Dipivefrinehydrochloride ; Dipivefrinhydrochloride ; Hydrochloride,(+-)-Este ; Propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ; Dipivefrin hydrochloride (200 Mg) ; (±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene dipivalate hydrochloride ; Dipivaloyl epinephrine hydrochloride
1. | orl-rat LD50:183 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
2. | ipr-rat LD50:8500 µg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
3. | scu-rat LD50:21,200 µg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
4. | orl-mus LD50:224 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
5. | ipr-mus LD50:32,700 µg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
6. | scu-mus LD50:35 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. | ||
7. | ivn-mus LD50:4 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 20 (1986),25. |
Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
Dipivefrin hydrochloride (64019-93-8) is a prodrug of adrenaline, which is used to treat glaucoma.It is available as ophthalmic solution .It causes vasoconstriction, decreased aqueous humor production, and decreases intraoccular pressure.It gets converted to epinephrine upon penetrating the cornea.