Detail of "64133-80-8"
- CAS Number:
- 64133-80-8
- Name:
Benzo[a]pyrene-6,12-dione,radical ion(1-) (9CI)
- Molecular Structure:
![Molecular Structure of 64133-80-8 (Benzo[a]pyrene-6,12-dione,radical ion(1-) (9CI))](http://www.lookchem.com/300w/20100309/64133-80-8.gif)
- Formula:
- C20H10 O2
Benzo[a]pyrene-6,12-dione,radical ion(1-) (9CI)
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Reference
- Binding of benzo[a]pyrene-semiquinone radicals with DNA and polynucleotides
- Binding of benzo[a]pyrene-semiquinone radicals with DNA and polynucleotides. Kodama, Masahiko; Ioki, Yoshikazu; Nagata, Chikayoshi (Biophys. Div., Natl. Cancer Cent. Res. Inst., Tokyo, Japan). Gann, 68(2), 253-4 (English) 1977. CODEN: GANNA2. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Results from EPR spectroscopy studies of the binding between several benzo[a]pyrene semiquinone anion radicals and DNA indicated that the 3,6-semiquinone radical [64133-78-4] covalently bound to DNA to the greatest extent, the 1,6-semiquinone radical [64133-79-5] bound 50% as much as the former radical, and no finding occurred for the 6,12-semiquinone radical [64133-80-8]. Bindings expts. of the radicals with polynucleotides detd. that the quanine residue was the site of binding. Linewidth and g-valve data of the bound complexes of the radicals and poly G indicated that the semiquinone radicals were the active species in binding to the base.