Reference

Studies on the mutagenicity of cosmetic azo-dyes

Studies on the mutagenicity of cosmetic azo-dyes. Miyagoshi, Mamoru; Hayakawa, Yumiko; Nagayama, Tomio (Tokyo Coll. 3118-97-6 and 6371-76-2 are also occured in this study. Pharm., Tokyo 192-03, Japan). Eisei Kagaku, 29(4), 212-20 (Japanese) 1983. CODEN: ESKGA2. ISSN: 0013-273X. DOCUMENT TYPE: Journal CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 4, 41 The cosmetic dyes Red 228 [2814-77-9] and Orange 203 [3468-63-1] were mutagenic, whereas Red 203 [2092-56-0], 204 [5160-02-1], 207 [1103-38-4], 221 [2425-85-6], and 505 [3118-97-6], Orange 205 [633-96-5], 403 [2646-17-5], and Yellow 401 [2512-29-0] were not. Some com. products contg. Red 201 [5858-81-1], 202 [5281-04-9], 219 [6371-76-2], and 220 [6417-83-0] were mutagenic, presumably due to contaminants. .

Color additives

Color additives. Anon. (Food Drug Adm., Washington, D. C., USA). Fed. Regist., 41(227), 51591-9, (English) 23 Nov 1976. CODEN: FEREAC. DOCUMENT TYPE: Journal CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 63 The following color additives, with information on identity and specifications, are permanently listed under the Federal Food, Drug, and Cosmetic Act for use in externally applied drugs and cosmetics: Ext. D and C Yellow No. 7 (di-Na salt of 8-hydroxy-5,7-dinitro-2-naphthalenesulfonic acid) [846-70-8], D and C Red No. 34 [Ca salt of 3-hydroxy-4-[(1-sulfo-2-naphthalenyl)azo]-2-naphthalenecarboxylic acid] [6417-83-0], and D and C Red No. 31 [Ca salt of 3-hydroxy-4-(phenylazo)-2-naphthalenecarboxylic acid] [6371-76-2]; and for externally applied cosmetics only: D and C Brown No. 1 [mixt. of Na salts of 4-[[5-[(dialkylphenyl)azo]-2,4-dihydroxyphenyl]azobenzenesulfonic acid with Me as the principle alkyl group] [1320-07-6], and Ext. D and C Violet No. 2 [mono-Na salt of 2-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthracenyl)amino]-5-methylbe nzenesulfonic acid] [4430-18-6].Except for chemicals metioned above, 1320-07-6 and 6417-83-0 are also used. .