Reference

Impact of phenoxymethylpenicillin, erythromycin, clindamycin and doxycycline on Streptococcus salivarius in the oropharynx

Impact of phenoxymethylpenicillin, erythromycin, clindamycin and doxycycline on Streptococcus salivarius in the oropharynx. Heimdahl, Anders; Nord, Carl Erik; Borthen, Lillemor (Dep. Oral Surg., Huddinge Univ. Hosp., Stockholm, Swed.). J. Antimicrob. Chemother., 13(5), 505-9 (English) 1984. CODEN: JACHDX. ISSN: 0305-7453. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) In subjects given phenoxymethylpenicillin [87-08-1], erythromycin stearate [643-22-1], clindamycin [18323-44-9], or doxycycline [564-25-0] (for 7 days, orally), phenoxymethylpenicillin and doxycycline only slightly suppressed the no. of S. salivarius in the oropharynx, whereas erythromycin and clindamycin markedly decreased them. An increased risk of colonization with group A streptococci following treatment with erythromycin or clindamycin is discussed.

Spectrophotometric estimation of erythromycin and its dosage forms

Spectrophotometric estimation of erythromycin and its dosage forms. Emmamuel, J.; Mathew, Roy (Pharm. Res. Lab., Goa Coll. Pharm., Goa 403 001, India). Indian Drugs, 22(3), 160-2 (English) 1984. CODEN: INDRBA. ISSN: 0019-462X. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Erythromycin (I) [114-07-8] was allowed to react with nitrobenzaldehyde [31620-90-3] in HOAc, and the absorbance of the resulting complex was measured at 490 nm. Beer's law was obeyed in the range 15-40 mg/mL. The title method was applied to detn. of I as erythromycin estolate [3521-62-8], erythromycin stearate [643-22-1], and erythromycin Et succinate [1264-62-6] with recoveries in the range 97.45-101.8%.