CAS No.64506-49-6,Sofalcone Suppliers

Products Categories

Pharmaceutical (74)
Organic Chemicals (26)
Others (16)
Reagent (2)
Basic Inorganic Chemicals (2)
Food Additives (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	64506-49-6
Name:	Sofalcone
Article Data:	1

Formula:	C₂₇H₃₀O₆
Molecular Weight:	450.532
Synonyms:	Aceticacid, [5-[(3-methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-(9CI);SU 88;Solon;
EINECS:	1308068-626-2
Density:	1.149 g/cm³
Melting Point:	143-144°
Boiling Point:	650 °C at 760 mmHg
Flash Point:	215.2 °C
PSA:	82.06000
LogP:	5.73610

Total:102 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 64506-49-6

Chemistry

Molecular Formula: C₂₇H₃₀O₆
Molecular Weight of Sofalcone (CAS NO.64506-49-6): 450.52
Flash Point: 215.2 °C
Index of Refraction: 1.578
Molar Refractivity: 130.2 cm³
Molar Volume: 391.8 cm³
Surface Tension: 43.7 dyne/cm
Density: 1.149 g/cm³
Boiling Point: 650 °C at 760 mmHg
Enthalpy of Vaporization: 100.68 kJ/mol
Vapour Pressure: 8.75E-18 mmHg at 25 °C
Structure of Sofalcone (CAS NO.64506-49-6):

IUPAC Name: 2-[5-(3-Methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-enoyl]phenoxy]acetic acid
Canonical SMILES: CC(=CCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
Isomeric SMILES: CC(=CCOC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
InChI: InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)/b12-7+
InChIKey: GFWRVVCDTLRWPK-KPKJPENVSA-N

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 20gm/kg (20000mg/kg)		Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
mouse	LD50	intraperitoneal	609mg/kg (609mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
mouse	LD50	intravenous	131mg/kg (131mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)		Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
mouse	LD50	subcutaneous	1130mg/kg (1130mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
rat	LD50	intraperitoneal	1680mg/kg (1680mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
rat	LD50	intravenous	105mg/kg (105mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
rat	LD50	oral	> 10gm/kg (10000mg/kg)		Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.
rat	LD50	subcutaneous	3900mg/kg (3900mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 61, 1982.

Safety Profile

Experimental teratogenic and reproductive effects. When heated to decomposition it emits acrid smoke and fumes.

Specification

Sofalcone , its cas register number is 64506-49-6. It also can be called SU 88 ; 2'-Carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone ; Sofalcona ; Solon ; and {5-[(3-Methyl-2-butenyl)oxy]-2-{p-[(3-methyl-2-butenyl)oxy]cinnamoyl}phenoxy}acetic acid . Sofalcone (CAS NO.64506-49-6) is an oral gastrointestinal medication. It is a synthetic derivative of sophoradin which is a polyphenol found in Sophora subprostrata (or Sophora tonkinensis ) as a herb used in traditional Chinese medicine.