Detail of "64953-12-4"

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CAS Number:
64953-12-4
Name:
5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-
Superlist Name:
Latamoxef sodium
Molecular Structure:
Formula:
C₂₀H₁₈N₆Na₂O₉S
Molecular Weight:
564.48
Synonyms:
5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;
Hazard Symbols:
Xn
Risk Codes:
42/43
Safety:
22-36/37-45 Details

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64953-12-45-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-
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629-19-6Disulfide, dipropyl

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CAS No.64953-12-4 Latamoxef sodium

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CAS No.64953-12-4 Latamoxef sodium

Assay:99%(min)

Chemical Name:Latamoxef sodium Alternative name: Moxalactam sodium salt; Disodium 7-[[carboxylato(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate M.F.:C20H18N6Na2O9S More info,pls c

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CAS No.64953-12-4 latamoxef sodium

Assay:99%min Appearance:white or lig... Package:Packed at th...

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CAS No.64953-12-4 Latamoxef sodium

Product Name: LATAMOXEF SODIUM We are the only factory who can supply API for this product. Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent in fringement and its liability is at buyer's risk

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CAS No.64953-12-4 Latamoxef sodium

Molecular Formula C20H18N6Na2O9S Molecular Weight 564.44 CAS Registry Number 64953-12-4 EINECS 265-288-4

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CAS No.64953-12-4 Latamoxef sodium

Synonyms: MOXALACTAM SODIUM SALT;5-oxa-1-azabicyclo(4.2.o)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen;6059s;antibiotic6059-s;disodiumlatamoxef;latamoxefsodium;ly127935;moxalactamdisodium CAS: 64953-12-4 MF: C20H18N6Na2O9S MW: 564.44 EINECS: 265-288-4

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Latamoxef Sodium

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Reference

Stability of metronidazole and ten antibiotics when mixed with magnesium sulphate solutions: Stability of metronidazole and ten antibiotics when mixed with magnesium sulphate solutions. Das Gupta, V.; Stewart, Kenneth R. (Coll. Pharm., Univ. Houston, Houston, TX 77030, USA). J. Clin. Hosp. Pharm., 10(1), 67-72 (English) 1985. CODEN: JCHPDS. ISSN: 0143-3180. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The chem. stabilities of metronidazole (I) [443-48-1] (in water) and 10 antibiotics, ampicillin [69-53-4], carbenicillin [4697-36-3], cefamandole naftate [42540-40-9], cefazolin [25953-19-9], cefoxitin [35607-66-0], moxalactam di-Na salt [64953-12-4], nafcillin Na salt [985-16-0], penicillin G [61-33-6], piperacillin Na salt [59703-84-3], and ticarcillin di-Na salt [29457-07-6] in 5% dextrose injection (except ampicillin which was in 0.9% NaCl) with MgSO4 were studied at 25°. The clarity of the solns. did not change in 20 h. The pH values of I, nafcillin and penicillin G solns. contg. MgSO4 were lower (at 0 and 20 h) by up to 1.2 units as compared with solns. without MgSO4. The decompn. of nafcillin and penicillin G solns. by MgSO4 was significant due to effect on the pH values of the solns.

Degradation and epimerization kinetics of moxalactam in aqueous solution: Degradation and epimerization kinetics of moxalactam in aqueous solution. Hashimoto, Naofumi; Tasaki, Takenobu; Tanaka, Hiroyoshi (Shionogi Res. Lab., Shionogi and Co., Ltd., Osaka 553, Japan). J. Pharm. Sci., 73(3), 369-73 (English) 1984. CODEN: JPMSAE. ISSN: 0022-3549. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 22 The kinetics of epimerization and degrdn. of moxalactam (I) [64952-97-2] in aq. soln. was investigated by HPLC. The pH-rate profiles of the degrdn. and epimerization were detd. sep. over the pH range of 1.0-11.5 at 37° and const. ionic strength 0.5. The degrdn. and simultaneous epimerization were followed by measuring both of the residual R- [64953-12-4] and S- [78037-39-5] epimers of I di-Na salt. A pseudo-1st-order kinetics was obsd. The degrdn. was subjected to H+ and OH- catalysis and influenced by the dissocn. of the side chain phenolic group. The epimerization rates were influenced significantly in the acidic region by the dissocn. of the side chain carboxylic acid group and in the basic region by OH- catalysis. The pH-degrdn. rate profile of I showed a min. degrdn. rate const. between pH 4.0 and 6. 64952-97-2 and 78037-39-5 which are cas registry numbers of substances are two of reagents here.0. The pH-epimerization rate profiles of I showed min. epimerization rate consts. at pH 7.0. The epimerization rate consts. of the R- and S-epimers were not very different. .

Detail of "64953-12-4"

5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-

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CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

CAS No.64953-12-4 Latamoxef sodium

Reference