Reference

4'-Phenoxybenzanilides

4'-Phenoxybenzanilides. Neubauer, Georgeta; Bibian, Stefan Cilianu; Funieru, Gabriela; Bozga, Elisabeta Raluca; Cunescu, Florentina; Popescu, Horia; Visan, Veronica (Institutul de Cercetari Chimico-Farmaceutice, Rom.). Rom.Chemicals with cas numbers 50-86-2 and 89013-51-4 also play role. RO 79286 B 30 Jul 1982, 6 pp. (Romanian). (Romania). CODEN: RUXXA3. CLASS: IC: C07C103-78; C07C043-20. APPLICATION: RO 80-100581 22 Mar 1980. DOCUMENT TYPE: Patent CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) Benzoic acids were treated with PCl3 and 4-amino-2-chlorophenyl 4-(1,1-dimethylpropyl)phenyl ether (I) to give amides II (R = H, halo, alkoxy, OH, alkyl; R1 = H, halo, NH2, NHAc, alkoxy, OH, alkyl; R2 = H, alkyl, alkoxy; R3 = H, OH, NO2, MeC6H4SO2NH, halo, alkoxy), useful as psychotropics (no data). Thus, 3,4,5-(MeO)3C6H2CO2H was treated with I and PCl3 in PhCl at reflux temp. to give II (R = R1 = R2 = OMe, R3 = H). .

Studies on urinary organic acids of SHRSP by glass capillary column GC/MS (Part III)

Studies on urinary organic acids of SHRSP by glass capillary column GC/MS (Part III). Morita, Masanori; Hayashi, Akira (Res. Lab. 621-54-5 and 65-85-0 are also occured in this study., Kinki Univ., Osaka, Japan). Koenshu - Iyo Masu Kenkyukai, 8, 263-6 (Japanese) 1983. CODEN: KIMKDN. DOCUMENT TYPE: Journal CA Section: 14 (Mammalian Pathological Biochemistry) At the onset of hypertension in 2-mo-old spontaneously hypertensive, stroke-prone rats (SHRSP), methylmalonic acid level in the urine was markedly increased but gradually decreased in the 3rd mo when the blood pressure reached a max. level. The levels of benzoic acid and 4-hydroxyphenylacetic acid were also increased, whereas that of 3-hydroxyphenylpropionic acid was decreased. The changes of org. acid concns. in urine may be related to some factors involved in the induction of hypertension. .