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Detail of "65277-42-1"

  • CAS Number:
  • 65277-42-1
  • Name:
  • Ketoconazole

  • Molecular Structure:
  • Formula:
  • C26H28Cl2H4O4
  • Molecular Weight:
  • 531.44 .
  • Deleted CAS:
  • 72093-26-6
  • Synonyms:
  • Ketoconazole [USAN:BAN:INN:JAN];Ketoconazol [INN-Spanish];1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine;Ketoconazole (JAN/USP);Nizoral (TN);KW-1414;(+-)-cis-1-Acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine;Nizoral;cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-diox olan- 4-yl)methoxy)phenyl)-piperazine;Prestwick_744;Fungarest;1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone;Fungoral;Ketoconazol;Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis-;Ketoderm;cis-1-Acetyl-4-[4-[2-(2,4-dichlorophenyl)-2-(1H-cmidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxy]phenyl]pipenazine;
  • EINECS:
  • 265-667-4
  • Density:
  • 1.38 cm3
  • Melting Point:
  • 146 °C
  • Boiling Point:
  • 753.4 °C at 760 mmHg
  • Flash Point:
  • 409.4 °C
  • Appearance:
  • White powder
  • Hazard Symbols:
  • ToxicT
  • Risk Codes:
  • 25-36/37/38-23/24/25
  • Safety:
  • 36-45-36/37/39-26 Details
  • Transport Information:
  • UN 2811 6.1/PG 3

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CAS No.65277-42-1 KetoconazoleCompetitive Product

Assay:99%  Appearance:white crysta...  Package:25kg/drumStorage:25kg  Transportation:by sea/air/e...  Application:pharmaceutic...

product name:Ketoconazole molecular formula:C26H28Cl2N4O4    formula weight:531.44 usage:used for the treatment of superficial and deep mycosis, such as skin and nails, ringworm, vaginal candidiasis, gastrointestinal fungal infections, etc., as well as systemic infection caus

Min. Order:1Kilogram

Supplier:Hubei Yuancheng Pharmaceutical Co.,Ltd [ China (Mainland)]

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CAS No.65277-42-1 KetoconazoleCompetitive Product

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Ketoconazole Quality Standard:USP32/EP6.0/BP2007

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CAS No.65277-42-1 KetoconazoleCompetitive Product

Ketoconazole is an anti-fungal medication in the same family of drugs as fluconazole, itraconazole and miconazole. It prevents growth of several types of fungi by preventing production of the membranes that surround fungal cells.

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CAS No.65277-42-1 Ketoconazole

Assay:99%  Appearance:white crysta...  Package:25kg/drum

Product: Ketoconazole M.F.: C26H28Cl2N4O4 M.W.: 531.44 Usage: For skin and deep mycosis, including skin and nail psoriasis (topical treatment ineffective), gastrointestinal yeast infections, topical vaginal Candida

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CAS No.65277-42-1 Ketoconazole

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CAS No.65277-42-1 Ketoconazole

Description White to off white crystalline powder. Solubility Practically insoluble in water; Freely soluble in methylene chloride, soluble in Methanol, sparingly soluble in alcohol Identification The I.R. absorption Spectrum

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CAS No.65277-42-1 Ketoconazole

  Appearance:white to off...

Molecular Formula:C26H28Cl2H4O4 Molecular Weight:531.44 . EINECS:265-667-4 Melting Point:148 - 152 C Flash Point:Considered to be not inflammable Solubility:Insoluble SOLVENT Risk Codes:R25 Details

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CAS No.65277-42-1 Ketoconazole

Assay:99%  Appearance:White crysta...  Package:25kg/drum  Transportation:EMS,DHL,by A...

Other name: fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral Assay: 99% Packing: 25kg/drum M.F.: C26H28Cl2N4O4 M.W.: 531.43 Reference standard: USP34 Appearance: White crystalline powder

Min. Order:100Kilogram

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CAS No.65277-42-1 Ketoconazole

Assay:99%  Appearance:white Crysta...  Package:25kgs/drumStorage:Stored in a ...

Ketoconazole Functions: Anti Fungal Shelf Life: Two years

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CAS No.65277-42-1 Ketoconazole

  Package:25kgs/drum, ...Storage:avoid heat a...

Product Name: KETOCONAZOLE Chemical Name: cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-diox olan- 4-yl)methoxy)phenyl)-piperazine Structural Formula: Molecular Formula: C26H28Cl2N4O4 Molecular Weight: 531.44 Quality Standard: m

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CAS No.65277-42-1 Ketoconazole

KETOCONAZOLE USP/EP

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CAS No.65277-42-1 Ketoconazole

Assay:99%  Appearance:white crysta...  Package:25kgStorage:--  Application:Pharmaceutic...

Name: ketoconazole CAS No: 65277-42-1;79156-75-5 Molecular Formula: C26H28Cl2N4O4 Molecular Weight: 531.4309 Purity:99% Character:white crystalline powder; odorless, tasteless. Usage:antifungal drugs

Min. Order:1Kilogram

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CAS No.65277-42-1 Ketoconazole

KETOCONAZOLE(POWDER) C26H28CL2N4O4 531.44 Description: Whitish crystall powder, oderless and tasteless. Indications: It is indicated in the treatment of the infections caused by dermatophytes and yeasts such as tinea manus, tinea pedi

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CAS No.65277-42-1 Ketoconazole

? Name: KETOCONAZOLE ? CAS Number:65277-42-1 ? Molecular Formula:C26H28Cl2H4O4 ? Molecular Weight:531.44 . ? EINECS:265-667-4 ? Melting Point:148 - 152 C ? Flash Point:Considered to be not inflammable ? Solubility:Insoluble SOLVENT < (slightly) ethanol acids, methan

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Reference

Structural changes in Candida albicans after ketoconazole treatment
Structural changes in Candida albicans after ketoconazole treatment. Borgers, Marcel (Dep. Life Sci., Janssen Pharm., Beerse, Belg.). Med. Publ. Found. Symp. Ser., 13(Oral Ther. Vaginal Candidosis), 43-9 (English) 1984. CODEN: MPFSDF. ISSN: 0260-0242. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 10 The effects of ketoconazole (I) [65277-42-1] on C. albicans were detd. morphol. after both in vitro and in vivo (rat with vaginal candidosis) exposure. The efficacy of oral I treatment in vaginal candidosis most probably resides in the ability of the drug to prevent further development of the invasive form of C. albicans and to compromise the viability of the growth arrested vegetative form.
Determination of D-saccharic acid and 6b-hydroxycortisol in urine as well as g-glutamyltranspeptidase in serum as a parameter for the activity of drug metabolism in intensive care patients
Determination of D-saccharic acid and 6b-hydroxycortisol in urine as well as g-glutamyltranspeptidase in serum as a parameter for the activity of drug metabolism in intensive care patients. Heinemeyer, G.; Roots, I.; Lestau, P.; Dennhardt, R. (Klin. Steglitz, Inst. Klin. Pharm., Berlin 1000/45, Fed. Rep. Ger.). Anaesthesiol. Intensivmed. (Berlin), 161(Dtsch. Anaesthesiekongr., Freie Vortr., 1982), 187-96 (German) 1984. CODEN: ANIMD2. ISSN: 0171-1814. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 2 Urinary levels of D-saccharic acid [87-73-0] and 6b-hydroxycortisol [53-35-0] as well as serum g-glutamyl transpeptidase [9046-27-9] activity were used as indicator for drugs with liver cytochrome P 450 [9035-51-2]-inducing activity in intensive care patients. Of the drugs tested, barbiturates such as pentobarbital [76-74-4], phenobarbital [50-06-6], and thiopental [76-75-5] or imidazole-antimycotics such as miconazole [22916-47-8] or ketoconazole [65277-42-1], or drugs such as cimetidine [51481-61-9] all increased urinary oxalic acid. Of the 3 indicators used, saccharic acid was the most specific indicator for enzyme induction.
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