Detail of "6537-80-0"

Reference

Quantitative direct evaluation, by thin-layer chromatograms, of samples of chlorogenic acid and other caffeic acid esters in fruits and vegetables

Quantitative direct evaluation, by thin-layer chromatograms, of samples of chlorogenic acid and other caffeic acid esters in fruits and vegetables. Hanefeld, Manfred; Herrmann, Karl (Tech. Univ. Hannover, Hannover, Ger.). Dtsch. Lebensm.-Rundsch., 72(11), 383-8 (German) 1976. CODEN: DLRUAJ. DOCUMENT TYPE: Journal CA Section: 17 (Foods) The main caffeic acid esters of plants (chlorogenic acid [327-97-9], neochlorogenic acid [906-33-2], rosmarinic acid [20283-92-5], dicaffeoyltartaric acid [6537-80-0]) can be detd. by direct simultaneous measurement on thin-layer plates with a chromatogram photometer. The method allows detn.Several substances with their cas registry numbers 20283-92-5 and 6537-80-0 may be metioned in this study. of >1 ppm and consists of extn. of the caffeic acid esters from plant material, polyamide column chromatog., elution with MeOH contg. 0.5% ammonia, chromatog. on cellulose thin-layer plates and measurement between 355 and 365 nm. The major caffeic acid ester in most fruits is neochlorogenic acid. Chlorogenic acid predominates in apples, pears, and strawberries, and is also the main caffeic acid ester in vegetables. Dicafeoyltartaric acid occurs in Compositae, such as lettuce, endive, and chicory; neochlorogenic acid is found only in dill, and rosmarinic acid in dill, sweet fennel, and spices of Labiatae. .

Catechol-Substituted l-Chicoric acid analogues as HIV integrase inhibitors

Catechol-Substituted l-Chicoric acid analogues as HIV integrase inhibitors. Lee, Jae Yeol; Yoon, Kwon Joong; Lee, Yong Sup (Division of Life Sciences, Korea Institute of Science & Technology, Seoul 130-650, S. Korea). Bioorganic & Medicinal Chemistry Letters, 13(24), 4331-4334 (English) 2003 Elsevier Science B.V.There are some reagents with their cas registry numbers 653572-66-8 and 6537-80-0 are used in this study. CODEN: BMCLE8. ISSN: 0960-894X. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1, 25 L-Chicoric acid and dicaffeoylquinic acids, isolated from plants, are well known potent inhibitors of HIV integrase, which catalyzes the integration of HIV DNA copy into the host cell DNA essential for the prodn. of progeny viruses. The common structural features of these inhibitors are caffeic acid derivs. connected to tartaric acid or quinic acid through ester bonds. In the present study, L-chicoric acid analogs I (n = 0, 1), II and III (X = O, NH) with catechol groups in place of caffeoyl groups were synthesized and tested as HIV integrase inhibitors. The inhibitory activities of I, II and III (IC50 = 3.8 - 23.6 mM) were compared to that of the parent L-chicoric acid (IC50 = 13.7 mM). .