CAS No.66211-46-9,1,2-Propanediol,3-amino-, (2R)- Suppliers

Detail of "66211-46-9"

CAS Number:

66211-46-9

Name:

1,2-Propanediol,3-amino-, (2R)-

Superlist Name:

(R)-3-Amino-1,2-propanediol

Molecular Structure:

Formula:

C₃H₉NO₂

Molecular Weight:

91.11

Synonyms:

1,2-Propanediol,3-amino-, (R)-;(2R)-2,3-Dihydroxypropylamine;(+)-3-Amino-1,2-propanediol;(2R)-3-Aminopropane-1,2-diol;(R)-(+)-3-Amino-1,2-propanediol;(R)-3-Aminopropane-1,2-diol;3-Amino-(2R)-1,2-propanediol;

Density:

1.181 g/cm³

Melting Point:

54-56 °C

Boiling Point:

266.7 °C at 760 mmHg

Flash Point:

115.1 °C

Appearance:

white to light yellow crystal powder

Hazard Symbols:

Risk Codes:

34-22

Safety:

26-36/37/39-45 Details

Transport Information:

UN 2735

Reference

Preparation of pyrimidopyrimidinones as kinase inhibitors: Preparation of pyrimidopyrimidinones as kinase inhibitors.Some chemicals with cas registry numbers like 651734-79-1 and 66211-46-9 are also used. Chivikas, Connolly Cleo J.; Deur, Christopher James; Hamby, James Marino; Hoyer, Denton Wade; Limberakis, Chris; Reed, Jessica Elizabeth; Schroeder, Mel Conrad; Taylor, Clarke (USA ). U.S. Pat. Appl. Publ. US 2004019210 A1 29 Jan 2004,44 pp. (English). (United States of America). CODEN: USXXCO. CLASS: ICM: C07D487-02. ICS: C07D475-02; C07D043-02. NCL: 544256000; 544257000; 544284000; 544350000; 544363000. APPLICATION: US 2003-621983 17 Jul 2003. PRIORITY: US 2002-PV398638 25 Jul 2002. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 This invention provides phenyl-substituted pyrimidopyrimidines, dihydropyrimidopyrimidines, pyridopyrimidines, naphthyridines, and pyridopyrazines of the general formula I [A = O, NH2, mono(or di)alkylamino, NHCONHR12 (wherein R12 = alkyl, alkylenecycloalkyl); B, C, D = CH, N (with the proviso that C and D are not both N); R1 = alkyl (optionally substituted by CO2H), (un)substituted Ph, CH2Ph, piperidinyl, etc.; R2 = H, Cl, F; R3 = H, Cl, F (at least one of R2 or R3 = F); R4 = H, OH, OMe, OEt (if R4 = H, R2 and R3 is not H); R5 = OMe, OEt; R6 = H, alkyl-NH2, O-alkyl-NH2, etc.] that inhibit cyclin-dependent kinase and tyrosine kinase enzymes, methods and intermediates for their synthesis, as well as pharmaceutical compns. and methods for their use in treating, inhibiting or preventing maladies assocd. with cell proliferative disorders, including angiogenesis, atherosclerosis, restenosis, and cancer (no biol. data given). Synthesis of 35 title compds. I is described. E.g., a multi-step synthesis of II was given. .

Detail of "66211-46-9"

1,2-Propanediol,3-amino-, (2R)-

Famous Chemical Enterprises

Related products

Other Products

Supplier Location

Business Type

Certificates

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

CAS No.66211-46-9 (R)-3-Amino-1,2-propanediol

Reference