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Detail of "6633-61-0"

  • CAS Number:
  • 6633-61-0
  • Name:
  • 5-Thiazolecarboxylicacid, 2-amino-, methyl ester

  • Superlist Name:
  • Methyl 2-aminothiazole-5-carboxylate
  • Molecular Structure:
  • Formula:
  • C5H6N2O2S
  • Molecular Weight:
  • 158.18
  • Synonyms:
  • 2-Amino-5-(methoxycarbonyl)thiazole;2-Aminothiazole-5-carboxylic acid methyl ester;Methyl 2-amino-5-thiazolecarboxylate;NSC 42123;
  • Density:
  • 1.408 g/cm3
  • Melting Point:
  • 182-186 °C
  • Boiling Point:
  • 298.7 °C at 760 mmHg
  • Flash Point:
  • 134.5 °C
  • Risk Codes:
  • 36/37/38
  • Safety:
  • 26-36/37/39 Details

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Changzhou Ansciep Chemical Co.,Ltd. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Assay:99.5%  Appearance:powder  Package:25kg/Cardboa...Storage:1-10MT

Supplier:Henan Tianfu Chemical Co., Ltd. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

  Package:in 25kgs car...Storage:normal condi...  Transportation:non dangerou...  Application:intermediate...

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:ShiJiaZhuang HuanQiu Chemicals Co.,Ltd [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Changzhou Wujin Qianhuang Sanyou Chemical Factory [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

5-Thiazolecarboxylic acid, 2-amino-, methyl ester

Supplier:Shanghai Chemical Pharm-Intermediate Tech.co.,ltd [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Assay:>98% HPLC  Package:1G,5G,10G,25...Storage:1G  Application:research

Supplier:BoRui Pharmaceuticals,Inc. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Assay:98%

Supplier:Wuhan Pharma Chemical Co., Ltd. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Methyl 2-aminothiazole-5-carboxylate

Supplier:Changzhou Harvest Chemistry Co., Ltd [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Methyl 2-aminothiazole-5-carboxylate

Supplier:T.H Chemicals Co.,Ltd, [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

0.98

Supplier:Holly MedchemCo., Ltd. [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

5-Thiazolecarboxylic acid, 2-amino-, methyl ester

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:NINGBO HI-TECH BIOCHEMICALS CO., LTD [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Shanghai Zuozhou Biology Science Co.,Ltd [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Shanghai Apichemical CO.,LTD [ China (Mainland)]

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CAS No.6633-61-0 Methyl 2-aminothiazole-5-carboxylate

Supplier:Quzhou Synpartner Pharmaceutical Technology Co.,Ltd. [ China (Mainland)]

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Reference

Preparation of pyrrolotriazine derivatives as kinase inhibitors
All Rights Reserved. Preparation of pyrrolotriazine derivatives as kinase inhibitors. Chen, Ping; Norris, Derek J.In this study, 918537-44-7 and 6633-61-0 are also used.; Gavai, Ashvinikumar V. (Bristol-Myers Squibb Company, USA). PCT Int. Appl. WO 2007005631 A1 11 Jan 2007, 58pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. APPLICATION: WO 2006-US25632 29 Jun 2006. PRIORITY: US 2005-696390P 1 Jul 2005; US 2005-696394P 1 Jul 2005; US 2005-703086P 28 Jul 2005. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 Title compds. represented by the formula I [wherein R1 = substituted pyrimidinyl or thiazolyl; R2 = H or alkyl; R3, R4 = independently H, alkyl, -OR9 or NR10R11; R5, R6 = independently (un)substituted alkyl or R5R6N = (un)substituted heterocyclyl; n = 2-6; R9 = H or (un)substituted alkyl(amino); R10, R11 = independently H or (un)substituted alkyl; and pharmaceutically acceptable salts thereof] were prepd. as kinase inhibitors. For example, II was provided in a multi-step synthesis starting from 6-hydroxy-5-methylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one. I have been tested in at least one assay, which is cell-based assay for Histone H3 phosphorylation, phenotypic anal. of cells treated with Aurora Kinase inhibitors, cell cytotoxicity assay and Murine biochem. assay. Thus, I and their pharmaceutical compns. are useful as kinase inhibitors for the treatment of proliferative disease, such as cancer. .
Studies on decarboxylation reactions
Studies on decarboxylation reactions.Some chemicals with cas registry numbers like 6633-61-0 and 133972-64-2 are also used. Part 7. Kinetic study of the decarboxylation of 2-amino- and 2-(phenylamino)-5-thiazolecarboxylic acids. [Erratum to document cited in CA114(25):246651a]. Noto, Renato; Ciofalo, Maurizio; Buccheri, Francesco; Werber, Giuseppe; Spinelli, Domenico (Dip. Chim. Org., Palermo 90123, Italy). J. Chem. Soc., Perkin Trans. 2, (2), 321 (English) 1992. CODEN: JCPKBH. ISSN: 0300-9580. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) A cor. Scheme 2 has been provided. The error was not reflected in the abstr. or the index entries. .
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