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67730-10-3

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Basic Information
CAS No.: 67730-10-3
Name: 2-AMINODIPYRIDO[1,2-A:3',2-D]IMIDAZOLE, HYDROCHLORIDE
Molecular Structure:
Molecular Structure of 67730-10-3 (2-AMINODIPYRIDO[1,2-A:3',2-D]IMIDAZOLE, HYDROCHLORIDE)
Formula: C10H8 N4
Molecular Weight: 184.2
Synonyms: Dipyrido[1,2-a:3',2'-d]imidazol-2-amine(9CI); 2-Aminodipyrido[1,2-a:3',2'-d]imidazole; Glu-P 2
Density: 1.47 g/cm3
Melting Point: 300oC
Boiling Point: 349.7 °C at 760 mmHg
Flash Point: 165.3 °C
Hazard Symbols: Xi
Safety: Confirmed carcinogen with experimental carcinogenic data. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
PSA: 56.21000
LogP: 2.84790
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Chemistry

Product Name: Glu-P-2
The MF of Glu-P-2 (CAS NO.67730-10-3) is C10H9ClN4.

               
The MW of Glu-P-2 (CAS NO.67730-10-3) is 220.66.
Synonyms of Glu-P-2 (CAS NO.67730-10-3): 2-Aminodipyridol[1,2-a:3',2'-d)]imidazole hydrochloride ; Glu-P-2 hydrochloride ; Pyrido[3',2':4,5]imidazo[1,2-a]pyridin-2-amine hydrochloride ; Imidazo[1,2-a:5,4-b']dipyridin-2-amine, hydrochloride
Product Categories: Mutagenesis Research Chemicals
Apperance: Crystalline Solid
Flash Point: 181.2 °C 
Boiling Point: 376 °C 
Melting Point: 300 °C

Uses

   Glu-P-2 (CAS NO.67730-10-3) is highly mutagenic in the Ames test. Studies have shown that broiled fish, fried beef, commercial beef extracts and protein pyrolsylates contain this mutagen.

Toxicity Data With Reference

1.    

mma-sat 100 ng/plate

     MUREAV    Mutation Research. 136 (1984),23.
2.    

pic-sat 10 µg/plate

     MUREAV    Mutation Research. 110 (1983),243.
3.    

sce-hmn:lym 10 µmol/L

     MUREAV    Mutation Research. 116 (1983),137.
4.    

dns-rat:lvr 1 µmol/L

     CALEDQ    Cancer Letters (Shannon, Ireland). 20 (1983),283.
5.    

dnd-mus:lvr 200 µmol/L

     JJCREP    Japanese Journal of Cancer Research (Gann). 76 (1985),835.
6.    

orl-rat TDLo:12,500 mg/kg/2Y-C:CAR,REP

     EVHPAZ    EHP, Environmental Health Perspectives. Subseries of DHEW Publications. 67 (1986),129.

Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 235.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Safety information of Glu-P-2 (CAS NO.67730-10-3):
Hazard Codes  IrritantXi