Detail of "67888-96-4"

CAS Number:
67888-96-4
Name:
1,1'-Biphenyl,2,2',4,5,5'-pentabromo-
Molecular Structure:
Formula:
C12H5 Br5
Molecular Weight:
548.6881
Synonyms:
2,2',4,5,5'-Pentabromo-1,1'-biphenyl;2,2',4,5,5'-Pentabromobiphenyl; 2,4,5,2',5'-Pentabromo-1,1'-biphenyl;2,4,5,2',5'-Pentabromobiphenyl; PBB 101
Density:
2.328 g/cm³
Boiling Point:
436.7ºC
Flash Point:
210.5ºC

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An in vitro model for the binding of polybrominated biphenyls in environmentally contaminated blood: An in vitro model for the binding of polybrominated biphenyls in environmentally contaminated blood. Roboz, John; Greaves, John; McCamish, Malcolm; Holland, James F.; Bekesi, George (Dep. Neoplast. Dis., Mount Sinai Sch. Med., New York, NY 10029, USA). Arch. Environ. Contam. Toxicol., 14(2), 137-42 (English) 1985. CODEN: AECTCV. ISSN: 0090-4341. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Spiking blood with 14C-labeled 2,2',4,4',5,5'-hexabromobiphenyl (I) [59080-40-9] or a mixt. of 2,2',4,5,5'-pentabromobiphenyl [67888-96-4], 2,2',4,5',6-pentabromobiphenyl [59080-39-6], and I was, in comparative measurements, a representative model of polybrominated biphenyl (PBB)-contaminated blood from Michigan residents. Blood components were obtained by Ficoll-Hypaque techniques, apolipoprotein B and A fractions by immunopptn. with specific antisera; congeners were quantified by neg. chem. ionization mass spectrometry or scintillation counting. The distribution of PBBs among plasma, erythrocytes, mononucleocytes, and polymorphonucleocytes was :￡1:￡1. In serum, 20% of the PBBs was not bound to protein. The remaining 80% was bound to apolipoproteins B and A in a 4:1 ratio, which is close to the ratio (by wt.) of the lipid content of these apolipoproteins. No preferential absorption of PBB congeners occurred in the examd. blood compartments.